Cited 0 times in
Survey of radiation field and dose in human papillomavirus-positive oropharyngeal cancer: is de-escalation actually applied in clinical practice?
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김준원 | - |
dc.date.accessioned | 2021-12-28T17:41:33Z | - |
dc.date.available | 2021-12-28T17:41:33Z | - |
dc.date.issued | 2021-09 | - |
dc.identifier.issn | 2234-1900 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187225 | - |
dc.description.abstract | Purpose: Studies on de-escalation in radiation therapy (RT) for human papillomavirus-related (HPV(+)) oropharyngeal cancer (OPC) are currently ongoing. This study investigated the current practice regarding the radiation dose and field in the treatment of HPV(+) OPC. Materials and methods: The Korean Society for Head and Neck Oncology conducted a questionnaire on the primary treatment policy. Among them, for HPV(+) OPC scenarios, radiation oncologists were questioned regarding the field and dose of RT. Results: Forty-two radiation oncologists responded to the survey. In definitive concurrent chemoradiotherapy (CCRT) treatment for stage T2N1M0 OPC, most respondents prescribed a dose of >60 Gy to the primary tonsil and involved ipsilateral lymph nodes. However, eight of the respondents prescribed a relatively low dose of ≤54 Gy. For stage T2N1M0 OPC, postoperative adjuvant RT was prescribed by eight and nine respondents with a lower dose of ≤50 Gy for the ipsilateral tonsil and involved neck, respectively. In definitive CCRT in complete remission after induction chemotherapy for initial stage T2N3M0 OPC, de-escalation of the tonsil and involved neck were performed by eight and seven respondents, respectively. Regarding whether de-escalation is applied in radiotherapy for HPV(+) OPC, 27 (64.3%) did not do it at present, and 15 (35.7%) were doing or considering it. Conclusion: The field and dose of prescribed treatment varied between institutions in Korea. Among them, dose de-escalation of RT in HPV(+) OPC was observed in approximately 20% of the respondents. Consensus guidelines will be set in the near future after the completion of ongoing prospective trials. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society for Therapeutic Radiology and Oncology | - |
dc.relation.isPartOf | RADIATION ONCOLOGY JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Survey of radiation field and dose in human papillomavirus-positive oropharyngeal cancer: is de-escalation actually applied in clinical practice? | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학교실) | - |
dc.contributor.googleauthor | Kyu Hye Choi | - |
dc.contributor.googleauthor | Jin Ho Song | - |
dc.contributor.googleauthor | Yeon-Sil Kim | - |
dc.contributor.googleauthor | Sung Ho Moon | - |
dc.contributor.googleauthor | Jeongshim Lee | - |
dc.contributor.googleauthor | Young-Taek Oh | - |
dc.contributor.googleauthor | Dongryul Oh | - |
dc.contributor.googleauthor | Jin Ho Kim | - |
dc.contributor.googleauthor | Jun Won Kim | - |
dc.identifier.doi | 10.3857/roj.2021.00556 | - |
dc.contributor.localId | A00958 | - |
dc.relation.journalcode | J02592 | - |
dc.identifier.eissn | 2234-3164 | - |
dc.identifier.pmid | 34610656 | - |
dc.subject.keyword | De-escalation | - |
dc.subject.keyword | Dose and Field | - |
dc.subject.keyword | Human papillomavirus | - |
dc.subject.keyword | Oropharyngeal cancer | - |
dc.subject.keyword | Radiotherapy | - |
dc.contributor.alternativeName | Kim, Jun Won | - |
dc.contributor.affiliatedAuthor | 김준원 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 174 | - |
dc.citation.endPage | 183 | - |
dc.identifier.bibliographicCitation | RADIATION ONCOLOGY JOURNAL, Vol.39(3) : 174-183, 2021-09 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.