Cited 0 times in
Minimally Invasive Versus Open Pancreatectomy for Right-Sided and Left-Sided G1/G2 Nonfunctioning Pancreatic Neuroendocrine Tumors: A Multicenter Matched Analysis with an Inverse Probability of Treatment-Weighting Method
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강창무 | - |
dc.contributor.author | 박준성 | - |
dc.contributor.author | 황호경 | - |
dc.date.accessioned | 2021-12-28T17:38:36Z | - |
dc.date.available | 2021-12-28T17:38:36Z | - |
dc.date.issued | 2021-11 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187200 | - |
dc.description.abstract | Background: Limited evidence exists for the safety and oncologic efficacy of minimally invasive surgery (MIS) for nonfunctioning pancreatic neuroendocrine tumors (NF-PNETs) according to tumor location. This study aimed to compare the surgical outcomes of MIS and open surgery (OS) for right- or left-sided NF-PNETs. Methods: The study collected data on patients who underwent surgical resection (pancreatoduodenectomy, distal/total/central pancreatectomy, duodenum-preserving pancreas head resection, or enucleation) of a localized NF-PNET between January 2000 and July 2017 at 14 institutions. The inverse probability of treatment-weighting method with propensity scores was used for analysis. Results: The study enrolled 859 patients: 478 OS and 381 MIS patients. A matched analysis by tumor location showed no differences in resection margin, intraoperative blood loss, or complications between MIS and OS. However, MIS was associated with a longer operation time for right-sided tumors (393.3 vs 316.7 min; P < 0.001) and a shorter postoperative hospital stay for left-sided tumors (8.9 vs 12.9 days; P < 0.01). The MIS group was associated with significantly higher survival rates than the OS group for right- and left-sided tumors, but survival did not differ for the patients divided by tumor grade and location. Multivariable analysis showed that MIS did not affect survival for any tumor location. Conclusion: The short-term outcomes offered by MIS were comparable with those of OS except for a longer operation time for right-sided NF-PNETs. The oncologic outcomes were not compromised by MIS regardless of tumor location or grade. These findings suggest that MIS can be performed safely for selected patients with localized NF-PNETs. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Minimally Invasive Surgical Procedures | - |
dc.subject.MESH | Neuroendocrine Tumors* / surgery | - |
dc.subject.MESH | Pancreatectomy | - |
dc.subject.MESH | Pancreatic Neoplasms* / surgery | - |
dc.subject.MESH | Pancreaticoduodenectomy | - |
dc.subject.MESH | Propensity Score | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Minimally Invasive Versus Open Pancreatectomy for Right-Sided and Left-Sided G1/G2 Nonfunctioning Pancreatic Neuroendocrine Tumors: A Multicenter Matched Analysis with an Inverse Probability of Treatment-Weighting Method | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Ho Kyoung Hwang | - |
dc.contributor.googleauthor | Ki Byung Song | - |
dc.contributor.googleauthor | Minsu Park | - |
dc.contributor.googleauthor | Wooil Kwon | - |
dc.contributor.googleauthor | Jin-Young Jang | - |
dc.contributor.googleauthor | Jin Seok Heo | - |
dc.contributor.googleauthor | Dong Wook Choi | - |
dc.contributor.googleauthor | Chang Moo Kang | - |
dc.contributor.googleauthor | Joon Seong Park | - |
dc.contributor.googleauthor | Tae Ho Hong | - |
dc.contributor.googleauthor | Chol Kyoon Cho | - |
dc.contributor.googleauthor | Keun Soo Ahn | - |
dc.contributor.googleauthor | Huisong Lee | - |
dc.contributor.googleauthor | Seung Eun Lee | - |
dc.contributor.googleauthor | Chi-Young Jeong | - |
dc.contributor.googleauthor | Young Hoon Roh | - |
dc.contributor.googleauthor | Hee Joon Kim | - |
dc.contributor.googleauthor | Dae Wook Hwang | - |
dc.contributor.googleauthor | Song Cheol Kim | - |
dc.contributor.googleauthor | Ho-Seong Han | - |
dc.contributor.googleauthor | Yoo-Seok Yoon | - |
dc.identifier.doi | 10.1245/s10434-021-10092-0 | - |
dc.contributor.localId | A00088 | - |
dc.contributor.localId | A01672 | - |
dc.contributor.localId | A04497 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 33969463 | - |
dc.identifier.url | https://link.springer.com/article/10.1245%2Fs10434-021-10092-0 | - |
dc.contributor.alternativeName | Kang, Chang Moo | - |
dc.contributor.affiliatedAuthor | 강창무 | - |
dc.contributor.affiliatedAuthor | 박준성 | - |
dc.contributor.affiliatedAuthor | 황호경 | - |
dc.citation.volume | 28 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 7742 | - |
dc.citation.endPage | 7758 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.28(12) : 7742-7758, 2021-11 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.