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Comparison of vaccine-induced thrombotic events between ChAdOx1 nCoV-19 and Ad26.COV.2.S vaccines
DC Field | Value | Language |
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dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2021-12-28T17:37:07Z | - |
dc.date.available | 2021-12-28T17:37:07Z | - |
dc.date.issued | 2021-08 | - |
dc.identifier.issn | 0896-8411 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/187186 | - |
dc.description.abstract | Cerebral venous thrombosis (CVT) events have been reported after vaccination with adenoviral COVID-19 vector vaccines. This study aimed to compare the clinical presentations and courses of vaccine-induced thrombotic thrombocytopenia (VITT) between the two adenoviral vector vaccines, Ad26.COV.2.S (Janssen/Johnson & Johnson) and ChAdOx1 nCoV-19 (Astra-Zeneca). We found that CVT after Ad26.COV.2.S vaccination presents later with similar symptoms compared to CVT after administration of ChAdOx1 nCoV-19, albeit with more thrombosis and intracerebral hemorrhage, lower D-dimer and aPTT levels but similar mortality. These findings could help guide clinical assessment and management of CVT after COVID-19 vaccination. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Academic Press | - |
dc.relation.isPartOf | JOURNAL OF AUTOIMMUNITY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | COVID-19 / prevention & control* | - |
dc.subject.MESH | COVID-19 Vaccines / adverse effects* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | SARS-CoV-2 | - |
dc.subject.MESH | Venous Thrombosis / epidemiology | - |
dc.subject.MESH | Venous Thrombosis / etiology* | - |
dc.title | Comparison of vaccine-induced thrombotic events between ChAdOx1 nCoV-19 and Ad26.COV.2.S vaccines | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Jimin Hwang | - |
dc.contributor.googleauthor | Se Bee Lee | - |
dc.contributor.googleauthor | Seung Won Lee | - |
dc.contributor.googleauthor | Min Ho Lee | - |
dc.contributor.googleauthor | Ai Koyanagi | - |
dc.contributor.googleauthor | Louis Jacob | - |
dc.contributor.googleauthor | Kalthoum Tizaoui | - |
dc.contributor.googleauthor | Dong Keon Yon | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.contributor.googleauthor | Lee Smith | - |
dc.identifier.doi | 10.1016/j.jaut.2021.102681 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J03722 | - |
dc.identifier.eissn | 1095-9157 | - |
dc.identifier.pmid | 34139631 | - |
dc.subject.keyword | Adenoviral vector vaccine | - |
dc.subject.keyword | COVID-19 vaccine | - |
dc.subject.keyword | Cerebral venous thrombosis | - |
dc.subject.keyword | Thrombotic thrombocytopenia syndrome | - |
dc.subject.keyword | Vaccine-induced thrombotic thrombocytopenia | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 122 | - |
dc.citation.startPage | 102681 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AUTOIMMUNITY, Vol.122 : 102681, 2021-08 | - |
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