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A Retrospective Comparison of Hemodynamic and Clinical Outcomes between Two Differently Designed Aortic Bioprostheses for Small Aortic Annuli

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dc.contributor.author유경종-
dc.contributor.author윤영남-
dc.contributor.author이삭-
dc.contributor.author이승현-
dc.contributor.author주현철-
dc.date.accessioned2021-12-28T17:05:19Z-
dc.date.available2021-12-28T17:05:19Z-
dc.date.issued2021-03-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/186928-
dc.description.abstractThe Trifecta valve has externally mounted leaflets; it differs from classic internally mounted valves (e.g., Carpentier-Edwards [C-E]). We evaluated post-implantation hemodynamics and clinical outcomes of these bioprostheses in small aortic annuli. From January 2015 to April 2019, 490 patients who underwent aortic valve replacement (AVR) were reviewed retrospectively. Altogether, 183 patients received 19 or 21 mm diameter C-E (n = 121) or Trifecta (n = 62) prostheses. To minimize confounding variables, we performed propensity-score matching analysis. The mean transvalvular pressure gradient (TVPG) was significantly lower in the Trifecta than in the C-E group at discharge (12.9 ± 4.8 vs. 15.0 ± 5.3 mmHg, p = 0.044). TVPG change over time was not significantly different between groups (p = 0.357). Left ventricular mass index decreased postoperatively (reduction: C-E, 28.1%; Trifecta, 30.1%, p = 0.879). No late mortality, severe patient-prosthesis mismatch, moderate-to-severe paravalvular leakage, structural valve degeneration, or valve thromboses were observed. Freedom from valve-related events at 3 years were similar for C-E (97.9% ± 2.1%) and Trifecta (97.7% ± 2.2%) patients (log-rank p = 0.993). Bioprosthesis design for small annuli significantly affected TVPG immediately after AVR. However, hemodynamics over time and clinical outcomes did not differ between the two designs.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleA Retrospective Comparison of Hemodynamic and Clinical Outcomes between Two Differently Designed Aortic Bioprostheses for Small Aortic Annuli-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic and Cardiovascular Surgery (흉부외과학교실)-
dc.contributor.googleauthorDo Jung Kim-
dc.contributor.googleauthorSak Lee-
dc.contributor.googleauthorHyun-Chel Joo-
dc.contributor.googleauthorYoung-Nam Youn-
dc.contributor.googleauthorKyung-Jong Yoo-
dc.contributor.googleauthorSeung Hyun Lee-
dc.identifier.doi10.3390/jcm10051063-
dc.contributor.localIdA02453-
dc.contributor.localIdA02576-
dc.contributor.localIdA02807-
dc.contributor.localIdA02935-
dc.contributor.localIdA03960-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid33806531-
dc.subject.keywordheart valve prosthesis implantation-
dc.subject.keywordhemodynamic monitoring-
dc.subject.keywordprosthesis design-
dc.subject.keywordsmall aortic annulus-
dc.contributor.alternativeNameYoo, Kyung Jong-
dc.contributor.affiliatedAuthor유경종-
dc.contributor.affiliatedAuthor윤영남-
dc.contributor.affiliatedAuthor이삭-
dc.contributor.affiliatedAuthor이승현-
dc.contributor.affiliatedAuthor주현철-
dc.citation.volume10-
dc.citation.number5-
dc.citation.startPage1063-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.10(5) : 1063, 2021-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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