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Cytokines in culture media of preimplantation embryos during in vitro fertilization: Impact on embryo quality
DC Field | Value | Language |
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dc.contributor.author | 김혜인 | - |
dc.contributor.author | 김희연 | - |
dc.contributor.author | 박윤정 | - |
dc.contributor.author | 박주현 | - |
dc.contributor.author | 백혜원 | - |
dc.contributor.author | 서석교 | - |
dc.contributor.author | 안소현 | - |
dc.contributor.author | 윤보현 | - |
dc.contributor.author | 이병석 | - |
dc.contributor.author | 이인하 | - |
dc.contributor.author | 이재훈 | - |
dc.contributor.author | 조시현 | - |
dc.contributor.author | 최영식 | - |
dc.date.accessioned | 2021-12-28T16:57:52Z | - |
dc.date.available | 2021-12-28T16:57:52Z | - |
dc.date.issued | 2021-12 | - |
dc.identifier.issn | 1043-4666 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186873 | - |
dc.description.abstract | Cytokine support of embryonic development includes promotion of implantation and protection of blastomeres from cell stress and apoptosis. Correlations between embryo quality and concentrations of specific cytokines in culture media of human embryos have been investigated for many years. The aim of this study was to assess the concentrations of cytokines in preimplantation embryo culture media and to investigate their relationships with embryo quality and in vitro fertilization (IVF) outcomes. Seventy-two samples were obtained from 39 infertile couples undergoing IVF or intracytoplasmic sperm injection treatment between October 2018 and May 2019. Each embryo was cultured separately, and the embryo culture medium was collected 72 h after fertilization. Before embryo transfer on day 3, a morphological evaluation of each embryo was performed. Cytokine concentrations of each culture medium were analyzed for 23 selected cytokines using the Multiplex Cytokine/Chemokine Panel II Assay (Merck Millipore®). The results were categorized into two groups (top-quality and non-top-quality embryos). The median age of the 39 patients was 34 years. Nine of 23 cytokines were quantified and compared between the top-quality embryo group and non-top-quality embryo group. Among the nine cytokines, CCL15, CCL27, and CXCL-12 were significantly elevated in the top-quality embryo group. These results suggested that specific cytokines measured in human embryo culture media can be used to predict embryo quality and IVF outcomes. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier B.V. | - |
dc.relation.isPartOf | CYTOKINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Cytokines in culture media of preimplantation embryos during in vitro fertilization: Impact on embryo quality | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics and Gynecology (산부인과학교실) | - |
dc.contributor.googleauthor | Inha Lee | - |
dc.contributor.googleauthor | So Hyun Ahn | - |
dc.contributor.googleauthor | Hye In Kim | - |
dc.contributor.googleauthor | Hye Won Baek | - |
dc.contributor.googleauthor | Yun Jeong Park | - |
dc.contributor.googleauthor | Heeyon Kim | - |
dc.contributor.googleauthor | Aminah Ibrahim Aljassim | - |
dc.contributor.googleauthor | Whan Shin | - |
dc.contributor.googleauthor | Chungsoon Ryu | - |
dc.contributor.googleauthor | Jeongmi Yoon | - |
dc.contributor.googleauthor | Jae Hoon Lee | - |
dc.contributor.googleauthor | Bo Hyon Yun | - |
dc.contributor.googleauthor | Seok Kyo Seo | - |
dc.contributor.googleauthor | Joo Hyun Park | - |
dc.contributor.googleauthor | Young Sik Choi | - |
dc.contributor.googleauthor | SiHyun Cho | - |
dc.contributor.googleauthor | Byung Seok Lee | - |
dc.identifier.doi | 10.1016/j.cyto.2021.155714 | - |
dc.contributor.localId | A05969 | - |
dc.contributor.localId | A06072 | - |
dc.contributor.localId | A06074 | - |
dc.contributor.localId | A01668 | - |
dc.contributor.localId | A05974 | - |
dc.contributor.localId | A01888 | - |
dc.contributor.localId | A05905 | - |
dc.contributor.localId | A02555 | - |
dc.contributor.localId | A02795 | - |
dc.contributor.localId | A05497 | - |
dc.contributor.localId | A04636 | - |
dc.contributor.localId | A03846 | - |
dc.contributor.localId | A04114 | - |
dc.relation.journalcode | J00691 | - |
dc.identifier.eissn | 1096-0023 | - |
dc.identifier.pmid | 34600304 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1043466621003033 | - |
dc.subject.keyword | CCL15 | - |
dc.subject.keyword | Cytokines | - |
dc.subject.keyword | Embryo culture medium | - |
dc.subject.keyword | Embryo quality | - |
dc.subject.keyword | IVF outcome | - |
dc.contributor.alternativeName | Kim, Hye In | - |
dc.contributor.affiliatedAuthor | 김혜인 | - |
dc.contributor.affiliatedAuthor | 김희연 | - |
dc.contributor.affiliatedAuthor | 박윤정 | - |
dc.contributor.affiliatedAuthor | 박주현 | - |
dc.contributor.affiliatedAuthor | 백혜원 | - |
dc.contributor.affiliatedAuthor | 서석교 | - |
dc.contributor.affiliatedAuthor | 안소현 | - |
dc.contributor.affiliatedAuthor | 윤보현 | - |
dc.contributor.affiliatedAuthor | 이병석 | - |
dc.contributor.affiliatedAuthor | 이인하 | - |
dc.contributor.affiliatedAuthor | 이재훈 | - |
dc.contributor.affiliatedAuthor | 조시현 | - |
dc.contributor.affiliatedAuthor | 최영식 | - |
dc.citation.volume | 148 | - |
dc.citation.startPage | 155714 | - |
dc.identifier.bibliographicCitation | CYTOKINE, Vol.148 : 155714, 2021-12 | - |
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