0 146

Cited 0 times in

Risk assessment of hepatocellular carcinoma and liver-related events using ultrasonography and transient elastography in patients with chronic hepatitis B

DC Field Value Language
dc.contributor.author김도영-
dc.contributor.author김범경-
dc.contributor.author김승업-
dc.contributor.author김자경-
dc.contributor.author박준용-
dc.contributor.author안상훈-
dc.contributor.author유성환-
dc.contributor.author이관식-
dc.contributor.author이재승-
dc.contributor.author이정일-
dc.contributor.author이현웅-
dc.contributor.author이혜원-
dc.contributor.author임태섭-
dc.contributor.author김도영-
dc.contributor.author김범경-
dc.contributor.author김승업-
dc.contributor.author김자경-
dc.contributor.author박준용-
dc.contributor.author안상훈-
dc.contributor.author유성환-
dc.contributor.author이관식-
dc.contributor.author이재승-
dc.contributor.author이정일-
dc.contributor.author이현웅-
dc.contributor.author이혜원-
dc.contributor.author임태섭-
dc.date.accessioned2021-12-28T16:51:46Z-
dc.date.available2021-12-28T16:51:46Z-
dc.date.issued2021-10-
dc.identifier.issn1352-0504-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/186827-
dc.description.abstractCirrhosis has prognostic value. We investigated whether the combined use of ultrasonography (US) and transient elastography (TE) to diagnose cirrhosis is beneficial for the risk assessment of hepatocellular carcinoma (HCC) and liver-related events in patients with chronic hepatitis B (CHB). A total of 9300 patients with CHB who underwent US and TE in two institutions between 2006 and 2018 were enrolled. TE value ≥13 kPa was set to indicate cirrhosis. Patients were divided into four groups: US(+)TE(+) (cirrhosis by US and TE), US(+)TE(-) (cirrhosis by US, but not by TE), US(-)TE(+) (cirrhosis by TE, but not by US) and US(-)TE(-) (non-cirrhosis by US and TE).The patients were predominantly male (n = 5474, 58.9%) with a mean age of 47.5 years. The proportions of patients with cirrhosis diagnosed by US and TE were 17.2% (n = 1595) and 13.2% (n = 1225), respectively. The proportion of patients with discordant results in diagnosing cirrhosis by US and TE was 18.7% (n = 1740). During follow-up (median: 60.0 months), HCC and liver-related events developed in 481 (5.2%) and 759 (8.2%) patients, respectively. The cumulative incidence rates of HCC and liver-related events were highest in the US(+)TE(+) group, intermediate-high in the US(-)TE(+) group, intermediate-low in the US(+)TE(-) group and lowest in the US(-)TE(-) group (overall p < .001). Cirrhosis assessed using US and TE was a major predictor of HCC and liver-related event development in patients with CHB. Cirrhosis assessed using TE seemed better in predicting HCC or liver-related events than using US, when cirrhosis diagnosis was discordant by US and TE.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherBlackwell Scientific Publications-
dc.relation.isPartOfJOURNAL OF VIRAL HEPATITIS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHCarcinoma, Hepatocellular* / diagnostic imaging-
dc.subject.MESHCarcinoma, Hepatocellular* / epidemiology-
dc.subject.MESHElasticity Imaging Techniques*-
dc.subject.MESHHepatitis B, Chronic* / complications-
dc.subject.MESHHumans-
dc.subject.MESHLiver Neoplasms* / diagnostic imaging-
dc.subject.MESHLiver Neoplasms* / epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRisk Assessment-
dc.subject.MESHUltrasonography-
dc.titleRisk assessment of hepatocellular carcinoma and liver-related events using ultrasonography and transient elastography in patients with chronic hepatitis B-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSung Hwan Yoo-
dc.contributor.googleauthorTae Seop Lim-
dc.contributor.googleauthorHyun Woong Lee-
dc.contributor.googleauthorJa Kyung Kim-
dc.contributor.googleauthorJae Seung Lee-
dc.contributor.googleauthorHye Won Lee-
dc.contributor.googleauthorBeom Kyung Kim-
dc.contributor.googleauthorJun Yong Park-
dc.contributor.googleauthorDo Young Kim-
dc.contributor.googleauthorSang Hoon Ahn-
dc.contributor.googleauthorJung Il Lee-
dc.contributor.googleauthorKwan Sik Lee-
dc.contributor.googleauthorSeung Up Kim-
dc.identifier.doi10.1111/jvh.13560-
dc.contributor.localIdA00385-
dc.contributor.localIdA00487-
dc.contributor.localIdA00654-
dc.contributor.localIdA00852-
dc.contributor.localIdA01675-
dc.contributor.localIdA02226-
dc.contributor.localIdA05883-
dc.contributor.localIdA02666-
dc.contributor.localIdA05963-
dc.contributor.localIdA03122-
dc.contributor.localIdA03292-
dc.contributor.localIdA03318-
dc.contributor.localIdA03414-
dc.contributor.localIdA00385-
dc.contributor.localIdA00487-
dc.contributor.localIdA00654-
dc.contributor.localIdA00852-
dc.contributor.localIdA01675-
dc.contributor.localIdA02226-
dc.contributor.localIdA05883-
dc.contributor.localIdA02666-
dc.contributor.localIdA05963-
dc.contributor.localIdA03122-
dc.contributor.localIdA03292-
dc.contributor.localIdA03318-
dc.contributor.localIdA03414-
dc.relation.journalcodeJ01928-
dc.identifier.eissn1365-2893-
dc.identifier.pmid34185929-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/10.1111/jvh.13560-
dc.subject.keywordchronic hepatitis B-
dc.subject.keywordhepatocellular carcinoma-
dc.subject.keywordliver cirrhosis-
dc.subject.keywordtransient elastography-
dc.subject.keywordultrasonography-
dc.contributor.alternativeNameKim, Do Young-
dc.contributor.affiliatedAuthor김도영-
dc.contributor.affiliatedAuthor김범경-
dc.contributor.affiliatedAuthor김승업-
dc.contributor.affiliatedAuthor김자경-
dc.contributor.affiliatedAuthor박준용-
dc.contributor.affiliatedAuthor안상훈-
dc.contributor.affiliatedAuthor유성환-
dc.contributor.affiliatedAuthor이관식-
dc.contributor.affiliatedAuthor이재승-
dc.contributor.affiliatedAuthor이정일-
dc.contributor.affiliatedAuthor이현웅-
dc.contributor.affiliatedAuthor이혜원-
dc.contributor.affiliatedAuthor임태섭-
dc.contributor.affiliatedAuthor김도영-
dc.contributor.affiliatedAuthor김범경-
dc.contributor.affiliatedAuthor김승업-
dc.contributor.affiliatedAuthor김자경-
dc.contributor.affiliatedAuthor박준용-
dc.contributor.affiliatedAuthor안상훈-
dc.contributor.affiliatedAuthor유성환-
dc.contributor.affiliatedAuthor이관식-
dc.contributor.affiliatedAuthor이재승-
dc.contributor.affiliatedAuthor이정일-
dc.contributor.affiliatedAuthor이현웅-
dc.contributor.affiliatedAuthor이혜원-
dc.contributor.affiliatedAuthor임태섭-
dc.citation.volume28-
dc.citation.number10-
dc.citation.startPage1362-
dc.citation.endPage1372-
dc.identifier.bibliographicCitationJOURNAL OF VIRAL HEPATITIS, Vol.28(10) : 1362-1372, 2021-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.