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Risk factors for unfavorable clinical outcomes in patients with brain abscess in South Korea

DC Field Value Language
dc.contributor.author구남수-
dc.contributor.author김무현-
dc.contributor.author김정호-
dc.contributor.author백예지-
dc.contributor.author손유진-
dc.contributor.author송영구-
dc.contributor.author안진영-
dc.contributor.author염준섭-
dc.contributor.author정수진-
dc.contributor.author조윤숙-
dc.contributor.author최준용-
dc.contributor.author현종훈-
dc.contributor.author구남수-
dc.contributor.author김무현-
dc.contributor.author김정호-
dc.contributor.author백예지-
dc.contributor.author손유진-
dc.contributor.author송영구-
dc.contributor.author안진영-
dc.contributor.author염준섭-
dc.contributor.author정수진-
dc.contributor.author조윤숙-
dc.contributor.author최준용-
dc.contributor.author현종훈-
dc.date.accessioned2021-12-28T16:45:21Z-
dc.date.available2021-12-28T16:45:21Z-
dc.date.issued2021-09-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/186786-
dc.description.abstractBackground: Brain abscess can be life-threatening and manifest various neurological findings, although the mortality rate has decreased recently. We investigated the risk factors for unfavorable outcomes of patients with brain abscess. Methods: A retrospective cohort study examined patients with brain abscess seen from May 2005 to December 2018 in a tertiary care hospital in Seoul, South Korea. We reviewed the medical records for clinical findings, therapeutic modalities, and prognostic factors of brain abscess. Unfavorable clinical outcomes were defined as death, moderate to severe disability with neurological deficits, or vegetative state at 1 year or at the time of discharge from outpatient follow-up. Results: The study enrolled 135 patients: 65.2% were males; the mean age was 56 years. 35.6% had unfavorable outcomes. In multivariate analysis, higher Sequential Organ Failure Assessment (SOFA) (p < 0.001), pre-existing hemiplegia (p = 0.049), and higher Charlson comorbidity index (CCI) (p = 0.028) were independently associated with unfavorable outcomes. Conclusions: Higher SOFA, pre-existing hemiplegia and higher Charlson comorbidity index were significant risk factors for unfavorable clinical outcomes in patients with brain abscess.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherPublic Library of Science-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAge Factors-
dc.subject.MESHAged-
dc.subject.MESHBrain Abscess / microbiology-
dc.subject.MESHBrain Abscess / mortality-
dc.subject.MESHBrain Abscess / pathology*-
dc.subject.MESHBrain Abscess / therapy-
dc.subject.MESHComorbidity-
dc.subject.MESHFemale-
dc.subject.MESHGram-Negative Bacteria / isolation & purification-
dc.subject.MESHGram-Positive Bacteria / isolation & purification-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHOrgan Dysfunction Scores-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTreatment Outcome*-
dc.titleRisk factors for unfavorable clinical outcomes in patients with brain abscess in South Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorYun Suk Cho-
dc.contributor.googleauthorYu Jin Sohn-
dc.contributor.googleauthorJong Hoon Hyun-
dc.contributor.googleauthorYae Jee Baek-
dc.contributor.googleauthorMoo Hyun Kim-
dc.contributor.googleauthorJung Ho Kim-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorJoon-Sup Yeom-
dc.contributor.googleauthorYoung Goo Song-
dc.identifier.doi10.1371/journal.pone.0257541-
dc.contributor.localIdA00189-
dc.contributor.localIdA04521-
dc.contributor.localIdA00902-
dc.contributor.localIdA05921-
dc.contributor.localIdA05924-
dc.contributor.localIdA02037-
dc.contributor.localIdA02267-
dc.contributor.localIdA02353-
dc.contributor.localIdA03638-
dc.contributor.localIdA05940-
dc.contributor.localIdA04191-
dc.contributor.localIdA05944-
dc.contributor.localIdA00189-
dc.contributor.localIdA04521-
dc.contributor.localIdA00902-
dc.contributor.localIdA05921-
dc.contributor.localIdA05924-
dc.contributor.localIdA02037-
dc.contributor.localIdA02267-
dc.contributor.localIdA02353-
dc.contributor.localIdA03638-
dc.contributor.localIdA05940-
dc.contributor.localIdA04191-
dc.contributor.localIdA05944-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid34543311-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김무현-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor백예지-
dc.contributor.affiliatedAuthor손유진-
dc.contributor.affiliatedAuthor송영구-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor조윤숙-
dc.contributor.affiliatedAuthor최준용-
dc.contributor.affiliatedAuthor현종훈-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김무현-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor백예지-
dc.contributor.affiliatedAuthor손유진-
dc.contributor.affiliatedAuthor송영구-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor조윤숙-
dc.contributor.affiliatedAuthor최준용-
dc.contributor.affiliatedAuthor현종훈-
dc.citation.volume16-
dc.citation.number9-
dc.citation.startPagee0257541-
dc.identifier.bibliographicCitationPLOS ONE, Vol.16(9) : e0257541, 2021-09-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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