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Oncologic Outcomes of Intracorporeal vs Extracorporeal Urinary Diversion After Robot-Assisted Radical Cystectomy: A Multi-Institutional Korean Study
DC Field | Value | Language |
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dc.contributor.author | 김종찬 | - |
dc.contributor.author | 나군호 | - |
dc.contributor.author | 한웅규 | - |
dc.contributor.author | 함원식 | - |
dc.date.accessioned | 2021-12-28T16:41:38Z | - |
dc.date.available | 2021-12-28T16:41:38Z | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 0892-7790 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186755 | - |
dc.description.abstract | Background: We aimed to compare the oncologic outcomes of intracorporeal urinary diversion (ICUD) and extracorporeal urinary diversion (ECUD) following robot-assisted radical cystectomy (RARC) in patients diagnosed with bladder cancer. Materials and Methods: Medical records of 730 patients who underwent RARC between April 2007 and May 2019 in 11 tertiary referral centers were retrospectively reviewed. We assessed recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) in the two groups using the Kaplan-Meier method. Cox regression models were used to identify factors associated with RFS, CSS, and OS. Results: Among 591 patients, neobladder diversion was performed more frequently in the ICUD group (70.8% vs 52.5%, p = 0.001). The median follow-up duration was shorter in the ICUD group than in the ECUD group (16 vs 26 months, p < 0.001). The rates of overall recurrence (36.5% vs 25.5%, p = 0.013) and pelvic recurrence (12.1% vs 5.9%, p = 0.031) were higher in the ECUD group. However, no differences in 5-year RFS (43.2% vs 58.4%, p = 0.516), CSS (79.3% vs 89.7%, p = 0.392), and OS (74.3% vs 81.4%, p = 0.411) were noted between the two groups. Multivariable analysis revealed that when compared to ICUD, ECUD was not associated with RFS (hazard ratio [HR], 0.982; p = 0.920), CSS (HR, 0.568; p = 0.126), and OS (HR, 0.642; p = 0.124). Conclusion: Although there was a difference in recurrence rate between the two groups, multivariable analysis indicated that the diversion technique after RARC did not affect the oncologic outcomes. Large prospective studies with long-term follow-up are warranted to verify the oncologic outcomes of ICUD and ECUD following RARC. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mary Ann Liebert | - |
dc.relation.isPartOf | JOURNAL OF ENDOUROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Cystectomy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neoplasm Recurrence, Local | - |
dc.subject.MESH | Postoperative Complications | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Robotic Surgical Procedures* | - |
dc.subject.MESH | Robotics* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Urinary Bladder Neoplasms* / surgery | - |
dc.subject.MESH | Urinary Diversion* | - |
dc.title | Oncologic Outcomes of Intracorporeal vs Extracorporeal Urinary Diversion After Robot-Assisted Radical Cystectomy: A Multi-Institutional Korean Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Won Sik Ham | - |
dc.contributor.googleauthor | Koon Ho Rha | - |
dc.contributor.googleauthor | Woong Kyu Han | - |
dc.contributor.googleauthor | Tae Gyun Kwon | - |
dc.contributor.googleauthor | Tae Hwan Kim | - |
dc.contributor.googleauthor | Seung Hyun Jeon | - |
dc.contributor.googleauthor | Sang Hyup Lee | - |
dc.contributor.googleauthor | Seok Ho Kang | - |
dc.contributor.googleauthor | Sung Gu Kang | - |
dc.contributor.googleauthor | Jong Kil Nam | - |
dc.contributor.googleauthor | Wansuk Kim | - |
dc.contributor.googleauthor | Byung Chang Jeong | - |
dc.contributor.googleauthor | Ja Hyun Ku | - |
dc.contributor.googleauthor | Jong Jin Oh | - |
dc.contributor.googleauthor | Sang Chul Lee | - |
dc.contributor.googleauthor | Ji Yeol Lee | - |
dc.contributor.googleauthor | Sung Hoo Hong | - |
dc.contributor.googleauthor | Young Goo Lee | - |
dc.contributor.googleauthor | Yong Seong Lee | - |
dc.contributor.googleauthor | Sung Yul Park | - |
dc.contributor.googleauthor | Young Eun Yoon | - |
dc.contributor.googleauthor | Jongchan Kim | - |
dc.identifier.doi | 10.1089/end.2021.0067 | - |
dc.contributor.localId | A04541 | - |
dc.contributor.localId | A01227 | - |
dc.contributor.localId | A04308 | - |
dc.contributor.localId | A04337 | - |
dc.relation.journalcode | J01394 | - |
dc.identifier.eissn | 1557-900X | - |
dc.identifier.pmid | 33678003 | - |
dc.identifier.url | https://www.liebertpub.com/doi/10.1089/end.2021.0067 | - |
dc.subject.keyword | cystectomy | - |
dc.subject.keyword | robotic surgical procedure | - |
dc.subject.keyword | urinary bladder neoplasm | - |
dc.subject.keyword | urinary diversion | - |
dc.contributor.alternativeName | Kim, Jong Chan | - |
dc.contributor.affiliatedAuthor | 김종찬 | - |
dc.contributor.affiliatedAuthor | 나군호 | - |
dc.contributor.affiliatedAuthor | 한웅규 | - |
dc.contributor.affiliatedAuthor | 함원식 | - |
dc.citation.volume | 35 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1490 | - |
dc.citation.endPage | 1497 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ENDOUROLOGY, Vol.35(10) : 1490-1497, 2021-10 | - |
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