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Prognosis and clinical relevance of recurrent oral ulceration in Behçet's disease

Authors
 D Bang  ;  W Hur  ;  E S Lee  ;  S Lee 
Citation
 JOURNAL OF DERMATOLOGY, Vol.22(12) : 926-929, 1995-12 
Journal Title
JOURNAL OF DERMATOLOGY
ISSN
 0385-2407 
Issue Date
1995-12
MeSH
Adolescent ; Adult ; Behcet Syndrome / complications ; Behcet Syndrome / diagnosis* ; Behcet Syndrome / physiopathology ; Child ; Child, Preschool ; Diagnosis, Differential ; Family Practice ; Female ; Humans ; Korea ; Male ; Middle Aged ; Mouth Diseases / complications ; Mouth Diseases / diagnosis* ; Mouth Diseases / physiopathology ; Prognosis ; Prospective Studies ; Recurrence ; Ulcer / complications ; Ulcer / diagnosis ; Ulcer / physiopathology
Abstract
There is no way of predicting whether a patient with recurrent oral ulcerations (ROU) will develop Behçet's disease (BD). In the absence of a valid laboratory test to exclude BD, such oral ulcerations result in a diagnostic problem when they occur as the sole and earliest manifestation of disease. We assessed the prognosis of ROU by performing prospective evaluations of 67 patients who had only a history of ROU and were registered at the Behçet's Disease Specialty Clinic at Severance Hospital of Yonsei University, Seoul, Korea. Thirty-five patients (52.2%) developed overt manifestations of BD at an average of 7.7 years after the onset of ROU. The frequency of recurrence was 9.8 times per year in progressive cases. From these results, it appears that highly recurrent ROU is a warning signal for BD. Careful examinations of patients, including their minor symptoms, additional laboratory tests, and regular follow-ups by physicians are required for proper diagnosis.
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1346-8138.1995.tb03947.x
DOI
10.1111/j.1346-8138.1995.tb03947.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Bang, Dong Sik(방동식)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/186675
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