자궁내막 증식증의 임상 병리학적 분석

Abstract

Endometrial hyperplasia is an abnormal proliferation, predominantly of the glandular component of the endometrium, which may progress to well differentiated carcinoma in a small percentage of women. Appropriate management of patients with endometrial hyperplasia depends on a number of clinical and pathologic factors. Recently, the International society of Gynecologic Pathologists, under the auspices of WHO, has developed a novel pathologic classification according to whether cytologic atypia is present. However, there have been few clinopathological study of endometrial hyperplasia by this classification. We have exprienced 107 cases with endometrial hyperplasia from January 1988 to December 1993. the age of the study subjects ranged from 27 to 71 years with a mean of 48.7 years. There were 51 cases with simple endometrial hyperplasia, 47 cases with complex hyperplasia and 9 cases with atypical endometrial hyperplasia. pregnancy was never experienced in 9 cases (8.4%) and the mean parity was 2.7. The most frequent complaint was metrorrhagia which was shown in 45 cases (42.1%) whereas postmenopausal bleeding in 9 cases(8.4%) and abdominal pain in 4 cases(3.7%) were observed. Out of the 51 cases with simple endometrial hyperplasia, 41 cases were treated by hysterectomy and 2 cases received hormone therapy. From 47 cases with complex hyperplasia , 42 patients had hysterectomy and only 1 case received hormone therapy. From 9 patients with atypical endometrial hyperplasia , 8 cases underwent hysterectomy and 1 case received hormone therapy.