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위암에서의 증식세포 핵항원(PCNA) 발현이 예후에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 노재경 | - |
dc.date.accessioned | 2021-12-27T17:14:44Z | - |
dc.date.available | 2021-12-27T17:14:44Z | - |
dc.date.issued | 1995-01 | - |
dc.identifier.issn | 0496-6872 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186495 | - |
dc.description.abstract | Proliferating cell nuclear antigen(PCNA) is known to be closely correlated with DNA synthesis and cell proliferation. Proliferative activities of tumors have recently been considered as one of important prognostic factors in a variety of human cancers. A total of 195 gastric carcinomas was evaluated with immunohistochemical study, using antibody(PC 10) with special reference to the correlation between PCNA expression and prognosis. PCNA expression was assessed semi-quantitatively based on the proportion of tumor cells with immunostained nuclei. There was no significant correlation between PCNA expression ad clinicopathological variables such as age, sex, tumor site, size, histologic grade, tumor stage, or the presence of lymph node metastases. To analyse survival, we evaluated disease-free survival and overall survival according to the extent of PCNA expression. No significant correlations between PCNA expression and both disease-free survival and overall survival were found. In conclusion, PCNA expression assessed by semi-quantitative PCNA grading system was not a significant prognostic factor in gastric carcinoma. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한암학회 | - |
dc.relation.isPartOf | Journal of the Korean Cancer Association(대한암학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 위암에서의 증식세포 핵항원(PCNA) 발현이 예후에 미치는 영향 | - |
dc.title.alternative | Prognostic Significance of Proliferating Cell Nuclear Antigen(PCNA) in Gastric Carcinoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 임호영 | - |
dc.contributor.googleauthor | 김주항 | - |
dc.contributor.googleauthor | 정현철 | - |
dc.contributor.googleauthor | 엄효동 | - |
dc.contributor.googleauthor | 최진혁 | - |
dc.contributor.googleauthor | 이기범 | - |
dc.contributor.googleauthor | 신동환 | - |
dc.contributor.googleauthor | 노재경 | - |
dc.contributor.googleauthor | 김병수 | - |
dc.contributor.localId | A01290 | - |
dc.relation.journalcode | J01813 | - |
dc.contributor.alternativeName | Roh, Jae Kyung | - |
dc.contributor.affiliatedAuthor | 노재경 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 18 | - |
dc.citation.endPage | 27 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Cancer Association (대한암학회지), Vol.27(1) : 18-27, 1995-01 | - |
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