신공여자와 수혜자사이의 체격불균형이 이식신의 단백뇨 발생에 미치는 영향

Abstract

Long-term renal graft losses are mainly due to chronic allograft dysfunction(CAD). In addition to immunologic factors, non-immunologic factors also contribute to CAD. It has recently been proposed that hyperfiltration from inadequate nephron dosing at the time of kidney transplantation(KT) plays an important role in CAD and donor kidney weight(KW)/recipient body weight(BW) ratio can be a surrogate marker for that mismatch. To investigate the influence of the mismatch of donor/recipient size on the CAD, we evaluated the effect of KW/BW ratio for the development of proteinuria and renal insufficiency.