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Evaluation of outcome of delayed neurologic sequlae after carbon monoxide poisoning by Techetium-99m Hexamethylpropylene Amine Oxime brain single photon emission computed tomography

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dc.contributor.author최영철-
dc.date.accessioned2021-12-27T17:13:40Z-
dc.date.available2021-12-27T17:13:40Z-
dc.date.issued1995-03-
dc.identifier.issn0014-3022-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/186482-
dc.description.abstractUsing brain computed tomography (CT) and single photon emission computed tomography (SPECT) with technetium-99m hexamethylpropylene amine oxime (99mTc HM-PAO) in 13 patients with delayed neurologic sequelae after carbon monoxide poisoning, we tried to evaluate the clinical outcome of delayed CO sequelae. Among the 13 initial brain CTs, seven showed low density in the cerebral white matter and one revealed hypodensity in both globi pallidi. Of the 7 follow-up CT scans, 3 have remained unchanged, but in 4 cases more aggravating patterns with cortical atrophy without the clinical correlation were observed. There was no correlation between the CT findings and the outcome of delayed CO sequelae. All initial SPECTs in 13 patients with delayed CO sequelae showed diffuse patchy hypoperfusion throughout the cerebral cortex. Among the follow-up SPECTs in 7 patients, 6 patients showed increased cerebral perfusion with the concomitant clinical improvement, but the SPECT of a patient in bedridden state had remained unchanged, compared with the initial SPECT. There seemed to be good correlation between the findings of SPECT and the outcome of delayed CO sequelae. In conclusion, 99mTc HM-PAO brain SPECT is more sensitive than CT, and may be a useful test in evaluating the clinical outcome of delayed neurologic sequelae after CO poisoning.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherKarger-
dc.relation.isPartOfEUROPEAN NEUROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAtrophy-
dc.subject.MESHBrain / blood supply*-
dc.subject.MESHBrain / pathology-
dc.subject.MESHBrain / physiopathology-
dc.subject.MESHBrain Damage, Chronic / diagnostic imaging*-
dc.subject.MESHBrain Damage, Chronic / physiopathology-
dc.subject.MESHBrain Mapping-
dc.subject.MESHCarbon Monoxide Poisoning / diagnostic imaging*-
dc.subject.MESHCarbon Monoxide Poisoning / physiopathology-
dc.subject.MESHCarboxyhemoglobin / metabolism-
dc.subject.MESHCerebral Cortex / blood supply-
dc.subject.MESHCerebral Cortex / pathology-
dc.subject.MESHCerebral Cortex / physiopathology-
dc.subject.MESHDisability Evaluation-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHGlobus Pallidus / blood supply-
dc.subject.MESHGlobus Pallidus / pathology-
dc.subject.MESHGlobus Pallidus / physiopathology-
dc.subject.MESHHumans-
dc.subject.MESHHypoxia, Brain / diagnostic imaging*-
dc.subject.MESHHypoxia, Brain / physiopathology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeurologic Examination*-
dc.subject.MESHOrganotechnetium Compounds-
dc.subject.MESHOximes-
dc.subject.MESHTechnetium Tc 99m Exametazime-
dc.subject.MESHTomography, Emission-Computed, Single-Photon*-
dc.titleEvaluation of outcome of delayed neurologic sequlae after carbon monoxide poisoning by Techetium-99m Hexamethylpropylene Amine Oxime brain single photon emission computed tomography-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurology (신경과학교실)-
dc.contributor.googleauthorChoi I.S.-
dc.contributor.googleauthorKim S.K.-
dc.contributor.googleauthorLee S.S.-
dc.contributor.googleauthorChoi Y.C.-
dc.identifier.doi10.1159/000117109-
dc.contributor.localIdA04116-
dc.relation.journalcodeJ00849-
dc.identifier.eissn1421-9913-
dc.identifier.pmid7628492-
dc.identifier.urlhttp://www.karger.com/Article/FullText/117109-
dc.contributor.alternativeNameChoi, Young Chul-
dc.contributor.affiliatedAuthor최영철-
dc.citation.volume35-
dc.citation.number3-
dc.citation.startPage137-
dc.citation.endPage142-
dc.identifier.bibliographicCitationEUROPEAN NEUROLOGY, Vol.35(3) : 137-142, 1995-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurology (신경과학교실) > 1. Journal Papers

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