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Prognostic factors and renal survival rates in IgA nephropathy
DC Field | Value | Language |
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dc.contributor.author | 강신욱 | - |
dc.contributor.author | 한대석 | - |
dc.date.accessioned | 2021-12-27T17:11:22Z | - |
dc.date.available | 2021-12-27T17:11:22Z | - |
dc.date.issued | 1995-03 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186452 | - |
dc.description.abstract | A retrospective study of 223 patients with IgA nephropathy (IgAN) was performed to clarify the prognostic factors and the renal survival rates of the disease. One hundred twenty-two patients were followed-up for more than 6 months after their renal biopsy (mean follow-up duration: 43.0 months), and 20 of them (16.4% ) had progressed to end-stage renal disease (ESRD). Using univariate analysis, 8 risk factors (2 clinical and 6 histopathological findings) for developing ESRD were identified: renal insufficiency at initial presentation (serum creatinine ≥ 1.5 mg/dl); heavy proteinuria(≥ 3.5 gm/day); moderate to severe histopathologic findings such as class IV/V lesions by W.H.O. classification, mesangial hypercellularity, glomerular sclerosis, interstitial infiltration, interstitial fibrosis, and tubular atrophy. In multivariate regression analysis, class IV/V lesions and renal insufficiency at initial presentation were the independent prognostic factors of IgAN. The renal survival rates were 100% at 1 year, 97.0% at 3 years, and 78.9% at 5 years. In conclusion, it seems that about 20% of IgAN patients have a risk to progress to ESRD within 5 years, and a careful follow-up is recommended especially in patients who have either renal insufficiency at the time of presentation or severe renal pathology (class IV/V lesions). | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adolescent | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Glomerulonephritis, IGA / complications* | - |
dc.subject.MESH | Glomerulonephritis, IGA / pathology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kidney Failure, Chronic / epidemiology* | - |
dc.subject.MESH | Kidney Failure, Chronic / etiology* | - |
dc.subject.MESH | Kidney Failure, Chronic / pathology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Prognostic factors and renal survival rates in IgA nephropathy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Shin Wook Kang | - |
dc.contributor.googleauthor | Kyu Hun Choi | - |
dc.contributor.googleauthor | Jong Hoon Park | - |
dc.contributor.googleauthor | Seung Woo Lee | - |
dc.contributor.googleauthor | Ho Yung Lee | - |
dc.contributor.googleauthor | Dae Suk Han | - |
dc.contributor.googleauthor | Soon Hee Seong | - |
dc.contributor.googleauthor | Hyeon Joo Jeong | - |
dc.contributor.googleauthor | In Joon Choi | - |
dc.identifier.doi | 10.3349/ymj.1995.36.1.45 | - |
dc.contributor.localId | A00053 | - |
dc.contributor.localId | A04272 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 7740835 | - |
dc.subject.keyword | IgA nephropathy | - |
dc.subject.keyword | Prognostic factor | - |
dc.subject.keyword | Renal survival rate | - |
dc.contributor.alternativeName | Kang, Shin Wook | - |
dc.contributor.affiliatedAuthor | 강신욱 | - |
dc.contributor.affiliatedAuthor | 한대석 | - |
dc.citation.volume | 36 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 45 | - |
dc.citation.endPage | 52 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.36(1) : 45-52, 1995-03 | - |
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