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Hypoxic contraction of isolated rat pulmonary artery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이영호 | - |
dc.date.accessioned | 2021-12-27T17:03:14Z | - |
dc.date.available | 2021-12-27T17:03:14Z | - |
dc.date.issued | 1995-12 | - |
dc.identifier.issn | 0916-8737 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186350 | - |
dc.description.abstract | The effects of hypoxia in precontracted rat pulmonary artery rings with and without endothelium was studied. Hypoxia (30 mmHg) produced a contraction (hypoxic pulmonary vasoconstriction, HPV). Removal of endothelium abolished the HPV. The HPV was reproducible. The amplitude of HPV was similar to arteries equilibrated with 100% O2 and room air. L-NNA markedly inhibited the HPV whereas indomethacin was ineffective. HPV was inhibited by caffeine, but not inhibited by nifedipine. It would be concluded that HPV in isolated rat pulmonary arteries is dependent on the endothelium and the mechanisms involved may be inhibition of basal NO production. | - |
dc.description.statementOfResponsibility | prohibition | - |
dc.language | English, Japanese | - |
dc.publisher | Dō Gakkai, Heisei 3 | - |
dc.relation.isPartOf | Journal of Smooth Muscle Research(Nihon Heikatsukin Gakkai kikanshi) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Caffeine / pharmacology | - |
dc.subject.MESH | Cell Hypoxia | - |
dc.subject.MESH | Cyclooxygenase Inhibitors / pharmacology | - |
dc.subject.MESH | Endothelium, Vascular / physiology | - |
dc.subject.MESH | In Vitro Techniques | - |
dc.subject.MESH | Indomethacin / pharmacology | - |
dc.subject.MESH | Nifedipine / pharmacology | - |
dc.subject.MESH | Nitric Oxide / biosynthesis | - |
dc.subject.MESH | Oxygen / metabolism* | - |
dc.subject.MESH | Pulmonary Artery / drug effects | - |
dc.subject.MESH | Pulmonary Artery / metabolism | - |
dc.subject.MESH | Pulmonary Artery / physiology* | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Vasoconstriction* / drug effects | - |
dc.subject.MESH | Vasodilator Agents / pharmacology | - |
dc.title | Hypoxic contraction of isolated rat pulmonary artery | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Physiology (생리학교실) | - |
dc.contributor.googleauthor | Y H Lee | - |
dc.contributor.googleauthor | H Y Lee | - |
dc.contributor.googleauthor | E Y Lee | - |
dc.contributor.googleauthor | B S Kang | - |
dc.contributor.localId | A02968 | - |
dc.relation.journalcode | J03851 | - |
dc.identifier.eissn | 1884-8796 | - |
dc.identifier.pmid | 8867976 | - |
dc.contributor.alternativeName | Lee, Young Ho | - |
dc.contributor.affiliatedAuthor | 이영호 | - |
dc.citation.volume | 31 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 471 | - |
dc.citation.endPage | 475 | - |
dc.identifier.bibliographicCitation | Journal of Smooth Muscle Research, Vol.31(6) : 471-475, 1995-12 | - |
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