자가면역 용혈성빈혈을 동반한 악성빈혈 1례

Abstract

Pernicious anemia appears to be autoimmune in origin. Autoantibodies such as anti-parietal cell antibody and anti-intrinsic factor antibody are found in about 90% and 70% of patients, respectively. It is commonly associated with autoimmune disorders of several organ systems, but rarely with autoimmune hemolytic anemia. When pernicious anemia and autoimmune hemolytic anemia occurs simultaneously, some diagnostic and therapeutic difficulties exist. We experienced a case of pernicious anemia associated with autoimmune hemolytic anemia. The patient was recovered by replacement of vitamin Bl2 and steroid therapy.