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모래쥐(Gerbil)에서 지속적 및 간헐적 뇌혈류차단의 뇌부종과 허혈성 신경세포 손상에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 주진양 | - |
dc.date.accessioned | 2021-12-27T16:45:44Z | - |
dc.date.available | 2021-12-27T16:45:44Z | - |
dc.date.issued | 1995-01 | - |
dc.identifier.issn | 1225-8245 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/186119 | - |
dc.description.abstract | Temporary occlusion of the cerebral blood flow is an effective maneuver to prevent and/or to control excessive bleeding during neurosurgical operations. Many studies have been reported employing single occlusion of various durations. However, there has been only a few studies examing the consequences of repeated occlusions on the development of cerebral edema and neuronal injury in the gerbil. Three separate episodes of 5-minute ischemia spaced at varied time interval was produced in Mongolian gerbils by occlusion of bilateral common carotid arteries. Quantitative estimates of cerebral edema and neuronal injury were obtained 24 hours after the third occlusion. The result was compared to that of single 15-minute occlusion. In gerbils with three 5-minute occlusions at 10-minute intervals, cerebral edema was not significant. However, the animals killed 24 hours after three 5-minute occlusions at 1-hour intervals or single 15-minute occlusion showed severe cerebral edema. Such animals showed significantly more neuronal injury than in animals with three 5-minute occlusions at 10-minute intervals. These results suggest that ischemic brain damage may be reduced with repeated vascular occlusions spaced at short intervals. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한신경외과학회 | - |
dc.relation.isPartOf | Journal of Korean Neurosurgical Society(대한신경외과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 모래쥐(Gerbil)에서 지속적 및 간헐적 뇌혈류차단의 뇌부종과 허혈성 신경세포 손상에 미치는 영향 | - |
dc.title.alternative | The Effects of Continuous and Intermittent Interruption of the Cerebral Blood Flow on Brain Edema and Ischemic Neuronal Injury in Gerbils. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | 전병윤 | - |
dc.contributor.googleauthor | 주진양 | - |
dc.contributor.googleauthor | 이규창 | - |
dc.contributor.googleauthor | 김태승 | - |
dc.contributor.localId | A03959 | - |
dc.relation.journalcode | J01521 | - |
dc.subject.keyword | Hypoxic neuronal injury | - |
dc.subject.keyword | Temporary occlusion | - |
dc.subject.keyword | Intermittent reperfusion | - |
dc.subject.keyword | Gerbil | - |
dc.contributor.alternativeName | Joo, Jin Yang | - |
dc.contributor.affiliatedAuthor | 주진양 | - |
dc.citation.volume | 24 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 753 | - |
dc.citation.endPage | 760 | - |
dc.identifier.bibliographicCitation | Journal of Korean Neurosurgical Society (대한신경외과학회지), Vol.24(7) : 753-760, 1995-01 | - |
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