62 73

Cited 0 times in

확진된 소아청소년 결핵에서 인터페론감마 분비검사의 진단적 가치

DC Field Value Language
dc.contributor.author강지만-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.contributor.author안종균-
dc.date.accessioned2021-11-19T01:37:04Z-
dc.date.available2021-11-19T01:37:04Z-
dc.date.issued2021-04-
dc.identifier.issn2384-1079-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/185945-
dc.description.abstractPurpose: This study aimed to evaluate the diagnostic value of the QuantiFERON-TB Gold In-Tube (QFT-GIT) in children with confirmed tuberculosis (TB). Methods: We retrospectively reviewed the medical records of children aged ≤18 years who underwent both QFT-GIT and Mycobacterium tuberculosis culture between 2006 and 2017. Confirmed TB was defined as the presence of at least one positive specimen for M. tuberculosis on culture or a nucleic acid amplification test. Results: Of the 582 patients included in the analysis, 48 were confirmed to have TB. The sensitivity and specificity of QFT-GIT for the diagnosis of confirmed TB were 85.4% and 95.5%, respectively. Among children with confirmed TB, the proportion in the immunocompromised state was higher in the QFT-GIT negative group than in the QFT-GIT positive group (50.0% vs. 5.7%, P=0.010). The median age at sampling was lower in the QFT-GIT indeterminate group than in the QFT-GIT positive group (7 years vs. 17 years, P=0.008), and the proportion of immunosuppression was higher in the QFT-GIT indeterminate group than in the QFT-GIT positive group (42.9% vs. 5.7%, P=0.017). The interferon gamma response to mitogen control was significantly higher in the 10-18 years group than in the 0-9 years group (P<0.001), and was significantly higher in the immunocompetent group than in the immunocompromised group (P=0.001). Conclusion: The QFT-GIT results should be interpreted carefully in immunocompromised or younger children suspected of having TB.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisherKorean Society of Pediatric Infectious Diseases-
dc.relation.isPartOfPediatric Infection & Vaccine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title확진된 소아청소년 결핵에서 인터페론감마 분비검사의 진단적 가치-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학교실)-
dc.contributor.googleauthor김규호-
dc.contributor.googleauthor강지만-
dc.contributor.googleauthor안종균-
dc.identifier.doi10.14776/piv.2021.28.e5-
dc.contributor.localIdA05720-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.contributor.localIdA02261-
dc.relation.journalcodeJ02486-
dc.identifier.eissn2384-1087-
dc.subject.keywordTuberculosis-
dc.subject.keywordInterferon-gamma release assay-
dc.subject.keywordChildren-
dc.contributor.alternativeNameKang, Ji-Man-
dc.contributor.affiliatedAuthor강지만-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.contributor.affiliatedAuthor안종균-
dc.citation.volume28-
dc.citation.number1-
dc.citation.startPage31-
dc.citation.endPage41-
dc.identifier.bibliographicCitationPediatric Infection & Vaccine, Vol.28(1) : 31-41, 2021-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.