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One-Year Change in the H 2 FPEF Score After Catheter Ablation of Atrial Fibrillation in Patients With a Normal Left Ventricular Systolic Function

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dc.contributor.author김태훈-
dc.contributor.author박희남-
dc.contributor.author엄재선-
dc.contributor.author유희태-
dc.contributor.author이문형-
dc.contributor.author정보영-
dc.date.accessioned2021-10-21T00:15:07Z-
dc.date.available2021-10-21T00:15:07Z-
dc.date.issued2021-08-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/185441-
dc.description.abstractBackground: It is unclear whether atrial fibrillation (AF) catheter ablation (AFCA) improves the left ventricular (LV) diastolic function. We evaluated the 1-year change in the H2FPEF score, which reflects the degree of LV diastolic function, after AFCA among patients with a normal LV systolic function. Methods and Results: We included 1,471 patients (30.7% female, median age 60 years, paroxysmal-type AF 68.6%) who had available H2FPEF scores at baseline and at 1-year after AFCA to evaluate the 1-year change in the H2FPEF score (ΔH2FPEF score[1-yr]) after AFCA. Baseline high H2FPEF scores (≥6) were independently associated with the female sex, left atrium (LA) diameter, LV mass index, pericardial fat volume, and a low estimated glomerular filtration rate. One year after AFCA, decreased ΔH2FPEF scores[1-yr] were associated with baseline H2FPEF scores of ≥6 [OR, 4.19 (95% CI, 2.88-6.11), p < 0.001], no diabetes [OR, 0.60 (95% CI, 0.37-0.98), p = 0.04], and lower pericardial fat volume [OR, 0.99 (95% CI, 0.99-1.00), p = 0.003]. Increased ΔH2FPEF scores[1-yr] were associated with a baseline H2FPEF score of <6 [OR, 3.54 (95% CI, 2.08-6.04), p < 0.001] and sustained AF after a recurrence within 1 year [SustainAF[1-yr]; OR, 1.89 (95% CI, 1.01-3.54), p = 0.048]. Throughout a 56-month median follow-up, an increased ΔH2FPEF score[1-yr] resulted in a poorer rhythm outcome of AFCA (at 1 year, log-rank p = 0.003; long-term, log-rank p = 0.010). Conclusions: AFCA appears to improve LV diastolic dysfunction. However, SustainAF[1-yr] may contribute to worsening LV diastolic dysfunction, and it was shown by increased ΔH2FPEF scores[1-yr], which was independently associated with higher risk of AF recurrence rate after AFCA. Clinical Trial Registration:ClinicalTrials.gov Identifier: NCT02138695.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherFrontiers Media S.A.-
dc.relation.isPartOfFRONTIERS IN CARDIOVASCULAR MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleOne-Year Change in the H 2 FPEF Score After Catheter Ablation of Atrial Fibrillation in Patients With a Normal Left Ventricular Systolic Function-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorMin Kim-
dc.contributor.googleauthorHee Tae Yu-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorJae-Sun Uhm-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorMoon-Hyoung Lee-
dc.contributor.googleauthorHui-Nam Pak-
dc.identifier.doi10.3389/fcvm.2021.699364-
dc.contributor.localIdA01085-
dc.contributor.localIdA01776-
dc.contributor.localIdA02337-
dc.contributor.localIdA02535-
dc.contributor.localIdA02766-
dc.contributor.localIdA03609-
dc.relation.journalcodeJ04002-
dc.identifier.eissn2297-055X-
dc.identifier.pmid34414218-
dc.subject.keywordatrial fibrillation-
dc.subject.keywordcatheter ablation-
dc.subject.keywordleft venticular diastolic dysfunction-
dc.subject.keywordrecurrent event-
dc.subject.keywordrisk score-
dc.contributor.alternativeNameKim, Tae-Hoon-
dc.contributor.affiliatedAuthor김태훈-
dc.contributor.affiliatedAuthor박희남-
dc.contributor.affiliatedAuthor엄재선-
dc.contributor.affiliatedAuthor유희태-
dc.contributor.affiliatedAuthor이문형-
dc.contributor.affiliatedAuthor정보영-
dc.citation.volume8-
dc.citation.startPage699364-
dc.identifier.bibliographicCitationFRONTIERS IN CARDIOVASCULAR MEDICINE, Vol.8 : 699364, 2021-08-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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