Cited 2 times in
Treatment Patterns and Clinical Outcomes in Korean Cancer Patients With Venous Thromboembolism: A Retrospective Cohort Study
DC Field | Value | Language |
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dc.contributor.author | 홍민희 | - |
dc.date.accessioned | 2021-10-21T00:07:01Z | - |
dc.date.available | 2021-10-21T00:07:01Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 1076-0296 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/185383 | - |
dc.description.abstract | This study assessed epidemiologic data and clinical outcomes, including venous thromboembolism (VTE) recurrence and bleeding events, in patients with cancer-associated VTE, and assessed factors associated with clinical outcomes. Data were extracted from retrospective medical-chart review of adult patients diagnosed with cancer-associated deep vein thrombosis or pulmonary embolism who received anticoagulation treatment for ≥3 months. Patients were classified by: low-molecular-weight heparin (LMWH), direct oral anticoagulants (DOACs), and other anticoagulants. First VTE recurrence and bleeding events, and factors associated with their occurrence, were assessed during the initial 6 months of treatment. Overall, 623 patients (age: 63.7 ± 11.3 years, 49.3% male) were included (119, 132, and 372 patients in LMWH, DOACs and other anticoagulants groups, respectively). The cumulative 6-month incidence of VTE recurrence was 16.6% (total), 8.3% (LMWH), 16.7% (DOACs), and 20.7% (other); respective bleeding events were 22.5%, 11.0%, 12.3%, and 30.7%). VTE recurrence and bleeding rates differed only between LMWH and other anticoagulants (HR 2.4, 95% CI: 1.2-5.0 and 3.6, 1.9-6.8, respectively). These results highlight the importance of initial VTE treatment choice for preventing VTE recurrence and bleeding events. LMWH or DOACs for ≥3 months can be considered for effective VTE management in cancer patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Sage Publications | - |
dc.relation.isPartOf | CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Administration, Oral | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Anticoagulants / administration & dosage | - |
dc.subject.MESH | Anticoagulants / adverse effects | - |
dc.subject.MESH | Anticoagulants / therapeutic use | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hemorrhage / etiology | - |
dc.subject.MESH | Heparin, Low-Molecular-Weight / therapeutic use | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasms / complications* | - |
dc.subject.MESH | Pulmonary Embolism / drug therapy | - |
dc.subject.MESH | Pulmonary Embolism / etiology | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Venous Thromboembolism / drug therapy* | - |
dc.subject.MESH | Venous Thromboembolism / etiology* | - |
dc.title | Treatment Patterns and Clinical Outcomes in Korean Cancer Patients With Venous Thromboembolism: A Retrospective Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Soo-Mee Bang | - |
dc.contributor.googleauthor | Jin-Hyoung Kang | - |
dc.contributor.googleauthor | Min Hee Hong | - |
dc.contributor.googleauthor | Jin-Seok Ahn | - |
dc.contributor.googleauthor | So Yeon Oh | - |
dc.contributor.googleauthor | Jin Ho Baek | - |
dc.contributor.googleauthor | Yoon Ji Choi | - |
dc.contributor.googleauthor | Seong Hoon Shin | - |
dc.contributor.googleauthor | Young-Joo Kim | - |
dc.contributor.googleauthor | Ha-Yeong Gil | - |
dc.contributor.googleauthor | Hyung-Eun Park | - |
dc.contributor.googleauthor | Juneyoung Lee | - |
dc.contributor.googleauthor | Eun-Lyeong Park | - |
dc.identifier.doi | 10.1177/1076029620979575 | - |
dc.contributor.localId | A04393 | - |
dc.relation.journalcode | J00546 | - |
dc.identifier.eissn | 1938-2723 | - |
dc.identifier.pmid | 33471574 | - |
dc.identifier.url | https://journals.sagepub.com/doi/10.1177/1076029620979575 | - |
dc.subject.keyword | cancer | - |
dc.subject.keyword | direct oral anticoagulants | - |
dc.subject.keyword | low-molecular-weight heparin | - |
dc.subject.keyword | venous thromboembolism | - |
dc.contributor.alternativeName | Hong, Min Hee | - |
dc.contributor.affiliatedAuthor | 홍민희 | - |
dc.citation.volume | 27 | - |
dc.citation.startPage | 1076029620979575 | - |
dc.identifier.bibliographicCitation | CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, Vol.27 : 1076029620979575, 2021-01 | - |
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