Cited 20 times in
Cardiovascular disease burden in adult patients with cancer: An 11-year nationwide population-based cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 강석민 | - |
dc.contributor.author | 김현창 | - |
dc.date.accessioned | 2021-10-21T00:05:07Z | - |
dc.date.available | 2021-10-21T00:05:07Z | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0167-5273 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/185368 | - |
dc.description.abstract | Background: Cardiovascular disease (CVD) is an important cause of morbidity and mortality in patients with cancer. However, the real-world CVD burden of adult cancer patients has not been well established. This study aimed to evaluate the prevalence and mortality of pre-existing and new-onset CVD in patients with cancers. Methods: We analysed the prevalence and mortality of pre-existing and new-onset CVD in 41,034 adult patients with ten common solid cancers in a single payer system using data from the Korean National Health Insurance Service-National Sample Cohort from 2002 to 2013. Results: When all types of cancer were included, 11.3% (n = 4647) of patients had pre-existing CVD when they were diagnosed with cancer. After excluding patients with pre-existing CVD, 15.7% of cancer patients (n = 5703) were newly diagnosed with CVD during the follow-up period (median 68 months). Both pre-existing and new-onset CVD were associated with increased risk of overall mortality and 5-year mortality. Multivariate analysis to predict all-cause mortality indicated both pre-existing and new-onset CVD, male sex, old age, prior history of diabetes or chronic kidney disease, suburban residential area, and low-income status as significant factors. Conclusions: Eleven percent of cancer patients had pre-existing CVD at the time of cancer diagnosis, and about 16% of cancer patients without pre-existing CVD were newly diagnosed with CVD, mostly within 5 years after the cancer diagnosis. Proper management of pre-existing CVD is necessary and pre-emptive prevention of new-onset CVD may alter treatment options and outcomes. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cardiovascular Diseases* / diagnosis | - |
dc.subject.MESH | Cardiovascular Diseases* / epidemiology | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Diabetes Mellitus* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Neoplasms* / diagnosis | - |
dc.subject.MESH | Neoplasms* / epidemiology | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Risk Factors | - |
dc.title | Cardiovascular disease burden in adult patients with cancer: An 11-year nationwide population-based cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jong-Chan Youn | - |
dc.contributor.googleauthor | Woo-Baek Chung | - |
dc.contributor.googleauthor | Justin A Ezekowitz | - |
dc.contributor.googleauthor | Jung Hwa Hong | - |
dc.contributor.googleauthor | Hyewon Nam | - |
dc.contributor.googleauthor | Dae-Sung Kyoung | - |
dc.contributor.googleauthor | In-Cheol Kim | - |
dc.contributor.googleauthor | Alexander R Lyon | - |
dc.contributor.googleauthor | Seok-Min Kang | - |
dc.contributor.googleauthor | Hae Ok Jung | - |
dc.contributor.googleauthor | Kiyuk Chang | - |
dc.contributor.googleauthor | Yong-Seog Oh | - |
dc.contributor.googleauthor | Ho-Joong Youn | - |
dc.contributor.googleauthor | Sang Hong Baek | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.identifier.doi | 10.1016/j.ijcard.2020.04.080 | - |
dc.contributor.localId | A00037 | - |
dc.contributor.localId | A01142 | - |
dc.relation.journalcode | J01093 | - |
dc.identifier.eissn | 1874-1754 | - |
dc.identifier.pmid | 32360647 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0167527320302606 | - |
dc.subject.keyword | Cancer | - |
dc.subject.keyword | Cardiovascular disease burden | - |
dc.subject.keyword | Mortality | - |
dc.subject.keyword | Population-based cohort | - |
dc.contributor.alternativeName | Kang, Seok Min | - |
dc.contributor.affiliatedAuthor | 강석민 | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.citation.volume | 317 | - |
dc.citation.startPage | 167 | - |
dc.citation.endPage | 173 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol.317 : 167-173, 2020-10 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.