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Physical and Biological Characteristics of Particle Therapy for Oncologists
DC Field | Value | Language |
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dc.contributor.author | 변화경 | - |
dc.contributor.author | 한민철 | - |
dc.contributor.author | 김진성 | - |
dc.contributor.author | 금웅섭 | - |
dc.contributor.author | 김용배 | - |
dc.date.accessioned | 2021-09-29T05:34:07Z | - |
dc.date.available | 2021-09-29T05:34:07Z | - |
dc.date.issued | 2021-07 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/185104 | - |
dc.description.abstract | Particle therapy is a promising and evolving modality of radiotherapy that can be used to treat tumors that are radioresistant to conventional photon beam radiotherapy. It has unique biological and physical advantages compared with conventional radiotherapy. The characteristic feature of particle therapy is the "Bragg peak," a steep and localized peak of dose, that enables precise delivery of the radiation dose to the tumor while effectively sparing normal organs. Especially, the charged particles (e.g., proton, helium, carbon) cause a high rate of energy loss along the track, thereby leading to high biological effectiveness, which makes particle therapy attractive. Using this property, the particle beam induces more severe DNA double-strand breaks than the photon beam, which is less influenced by the oxygen level. This review describes the general biological and physical aspects of particle therapy for oncologists, including non-radiation oncologists and beginners in the field. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Korean | - |
dc.publisher | Official journal of Korean Cancer Association | - |
dc.relation.isPartOf | CANCER RESEARCH AND TREATMENT | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Physical and Biological Characteristics of Particle Therapy for Oncologists | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학교실) | - |
dc.contributor.googleauthor | Hwa Kyung Byun | - |
dc.contributor.googleauthor | Min Cheol Han | - |
dc.contributor.googleauthor | Kyungmi Yang | - |
dc.contributor.googleauthor | Jin Sung Kim | - |
dc.contributor.googleauthor | Gyu Sang Yoo | - |
dc.contributor.googleauthor | Woong Sub Koom | - |
dc.contributor.googleauthor | Yong Bae Kim | - |
dc.identifier.doi | 10.4143/crt.2021.066 | - |
dc.contributor.localId | A05136 | - |
dc.contributor.localId | A05870 | - |
dc.contributor.localId | A04548 | - |
dc.contributor.localId | A00273 | - |
dc.contributor.localId | A00744 | - |
dc.relation.journalcode | J00453 | - |
dc.identifier.eissn | 2005-9256 | - |
dc.identifier.pmid | 34139805 | - |
dc.subject.keyword | Neoplasms | - |
dc.subject.keyword | Particle therapy | - |
dc.subject.keyword | Radiation injuries | - |
dc.subject.keyword | Radiotherapy | - |
dc.contributor.alternativeName | Byun, Hwa Kyung | - |
dc.contributor.affiliatedAuthor | 변화경 | - |
dc.contributor.affiliatedAuthor | 한민철 | - |
dc.contributor.affiliatedAuthor | 김진성 | - |
dc.contributor.affiliatedAuthor | 금웅섭 | - |
dc.contributor.affiliatedAuthor | 김용배 | - |
dc.citation.volume | 53 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 611 | - |
dc.citation.endPage | 620 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, Vol.53(3) : 611-620, 2021-07 | - |
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