Cited 3 times in
Update on Pathologic and Radiologic Diagnosis of Combined Hepatocellular-Cholangiocarcinoma
DC Field | Value | Language |
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dc.contributor.author | 박영년 | - |
dc.date.accessioned | 2021-09-29T01:34:39Z | - |
dc.date.available | 2021-09-29T01:34:39Z | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 2288-8128 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184435 | - |
dc.description.abstract | Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a malignant primary liver carcinoma characterized by the unequivocal presence of both hepatocytic and cholangiocytic differentiation within the same tumor. Recent research has highlighted that cHCC-CCAs are more heterogeneous than previously expected. In the updated consensus terminology and WHO 2019 classification, “classical type” and “subtypes with stem-cell features” of the WHO 2010 classification are no longer recommended. Instead, it is recommended that the presence and percentages of various histopathologic components and stem-cell features be mentioned in the pathologic report. The new terminology and classification enable the exchange of clearer and more objective information about cHCC-CCAs, facilitating multi-center and multi-national research. However, there are limitations to the diagnosis of cHCC-CCA by imaging and biopsy. cHCC-CCAs showing typical imaging findings of HCC could be misdiagnosed as HCC and subjected to inappropriate treatment, if other clinical findings are not sufficiently considered. cHCC-CCAs showing at least one of the CCA-like imaging features or unusual clinical features should be subjected to biopsy. There may be a sampling error for the biopsy diagnosis of cHCC-CCA. An optimized diagnostic algorithm integrating clinical, radiological, and histopathologic information of biopsy is required to resolve these diagnostic pitfalls. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한간암학회 | - |
dc.relation.isPartOf | Journal of Liver Cancer(대한간암학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Update on Pathologic and Radiologic Diagnosis of Combined Hepatocellular-Cholangiocarcinoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Hyungjin Rhee | - |
dc.contributor.googleauthor | Jae Hyon Park | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.identifier.doi | 10.17998/jlc.21.1.12 | - |
dc.contributor.localId | A01563 | - |
dc.relation.journalcode | J03078 | - |
dc.identifier.eissn | 2383-5001 | - |
dc.subject.keyword | Liver neoplasm | - |
dc.subject.keyword | Diagnosis | - |
dc.subject.keyword | Stem cell | - |
dc.subject.keyword | Magnetic resonance imaging | - |
dc.subject.keyword | Biopsy | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | 박영년 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 12 | - |
dc.citation.endPage | 24 | - |
dc.identifier.bibliographicCitation | Journal of Liver Cancer(대한간암학회지), Vol.21(1) : 12-24, 2021-03 | - |
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