Cited 20 times in
Reappraisal of pathological features of intraductal papillary neoplasm of bile duct with respect to the type 1 and 2 subclassifications
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박영년 | - |
dc.date.accessioned | 2021-09-29T01:29:14Z | - |
dc.date.available | 2021-09-29T01:29:14Z | - |
dc.date.issued | 2021-05 | - |
dc.identifier.issn | 0046-8177 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184388 | - |
dc.description.abstract | The pathological spectrum of intraductal papillary neoplasm of bile duct (IPNB) remains to be clarified. A total of 186 IPNBs were pathologically examined using the type 1 and 2 subclassifications proposed by Japanese and Korean biliary pathologists incorporating a two-tiered grading system (low-grade and high-grade dysplasia), with reference to four subtypes (intestinal [i], gastric [g], pancreatobiliary [pb], and concocytic [o] subtype). IPNBs were classifiable into type 1 composed of low-grade dysplasia and 'high-grade dysplasia with regular structures' (69 IPNBs), and type 2 of 'high grade dysplasia with irregular structures and complicated lesions' (117 IPNBs). Type 1 was more common in the intrahepatic bile duct (78%), whereas type 2 was frequently located in the extrahepatic bile duct (58%). Mucin hypersecretion was more common in type 1 (61%) than in type 2 (37%). IPNBs were classifiable into the four subtypes: 86 iPNBs, 40 gIPNBs, 31 pbIPNBs, and 29 oIPNBs. The four subtypes were histologically evaluable with reference to the type 1 and 2 subclassifications. iIPNB and pbIPNBs were frequently classified as type 2, whereas types 1 and 2 were observed at similar rates in gIPNB and oIPNB. Stromal invasion was almost absent in type 1, irrespective of subtype, but was found in 66 of 117 type 2 IPNBs (P < .01), and postoperative outcome was favorable in IPNBs without invasion compared with IPNBs with invasion (P < .05). The type 1 and 2 subclassifications with reference to the four subtypes may provide useful information for understanding IPNB. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | W B Saunders | - |
dc.relation.isPartOf | HUMAN PATHOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Reappraisal of pathological features of intraductal papillary neoplasm of bile duct with respect to the type 1 and 2 subclassifications | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Yasuni Nakanuma | - |
dc.contributor.googleauthor | Katsuhiko Uesaka | - |
dc.contributor.googleauthor | Yukiyasu Okamura | - |
dc.contributor.googleauthor | Takuro Terada | - |
dc.contributor.googleauthor | Yuki Fukumura | - |
dc.contributor.googleauthor | Yuko Kakuda | - |
dc.contributor.googleauthor | Takashi Sugino | - |
dc.contributor.googleauthor | Yasunori Sato | - |
dc.contributor.googleauthor | Jang Kee Taek | - |
dc.contributor.googleauthor | Young Nyun Park | - |
dc.identifier.doi | 10.1016/j.humpath.2021.01.002 | - |
dc.contributor.localId | A01563 | - |
dc.relation.journalcode | J01011 | - |
dc.identifier.eissn | 1532-8392 | - |
dc.identifier.pmid | 33508254 | - |
dc.subject.keyword | Biliary tree | - |
dc.subject.keyword | Intraductal papillary neoplasm of bile duct | - |
dc.subject.keyword | Pancreas | - |
dc.subject.keyword | Subclassification | - |
dc.subject.keyword | Subtype | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.affiliatedAuthor | 박영년 | - |
dc.citation.volume | 111 | - |
dc.citation.startPage | 21 | - |
dc.citation.endPage | 35 | - |
dc.identifier.bibliographicCitation | HUMAN PATHOLOGY, Vol.111 : 21-35, 2021-05 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.