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Slow Mohs Micrographic Surgery for Acral Melanoma Treatment in Korean Patients

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dc.contributor.author김상겸-
dc.contributor.author노미령-
dc.contributor.author서지명-
dc.contributor.author오영주-
dc.contributor.author정기양-
dc.contributor.author노미령-
dc.contributor.author서지명-
dc.contributor.author오영주-
dc.contributor.author정기양-
dc.date.accessioned2021-09-29T01:00:58Z-
dc.date.available2021-09-29T01:00:58Z-
dc.date.issued2021-02-
dc.identifier.issn1076-0512-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/184146-
dc.description.abstractBackground: Obtaining conventional wide surgical margins is challenging in melanomas occurring at anatomically complex sites (e.g., hands and feet). Objective: We investigated the potential benefits of slow Mohs micrographic surgery (MMS) for acral melanomas. Materials and methods: This single-center retrospective study investigated 210 patients who underwent slow MMS (n = 66) or wide local excision (WLE, n = 144) for melanomas during 2005 to 2015. Slow MMS was used for melanomas in anatomically complex locations and for high-risk lesions. Results: Acral melanoma (166/210) was the most common lesion observed in patients, in addition to head and neck (21/210) and trunk (23/210) melanomas. Slow MMS was more commonly performed for acral, and head and neck melanomas (32.5% and 52.4%, respectively) than for trunk melanomas (4.3%, p = .002). Local recurrence of acral melanomas occurred in 3.7% of patients after slow MMS and in 10.7% of patients after WLE. Multivariate analysis showed comparable prognostic outcomes between slow MMS and WLE used for acral melanomas. Compared with WLE, slow MMS resulted in a smaller postoperative defect after acral lesion excision (p < .001). Conclusion: Slow MMS is an effective alternative to WLE for acral melanomas in anatomically complex sites, as evidenced by superior outcomes and maximum tissue conservation.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherLippincott, Williams & Wilkins-
dc.relation.isPartOfDERMATOLOGIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHFoot-
dc.subject.MESHHand-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMargins of Excision-
dc.subject.MESHMelanoma / diagnosis-
dc.subject.MESHMelanoma / mortality-
dc.subject.MESHMelanoma / pathology-
dc.subject.MESHMelanoma / surgery*-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMohs Surgery / methods*-
dc.subject.MESHNeoplasm Recurrence, Local / epidemiology*-
dc.subject.MESHNeoplasm Recurrence, Local / pathology-
dc.subject.MESHNeoplasm Recurrence, Local / prevention & control-
dc.subject.MESHRepublic of Korea / epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSkin / pathology-
dc.subject.MESHSkin Neoplasms / diagnosis-
dc.subject.MESHSkin Neoplasms / mortality-
dc.subject.MESHSkin Neoplasms / pathology-
dc.subject.MESHSkin Neoplasms / surgery*-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTorso-
dc.titleSlow Mohs Micrographic Surgery for Acral Melanoma Treatment in Korean Patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학교실)-
dc.contributor.googleauthorJimyung Seo-
dc.contributor.googleauthorYeongjoo Oh-
dc.contributor.googleauthorSang Kyum Kim-
dc.contributor.googleauthorMi Ryung Roh-
dc.contributor.googleauthorKee Yang Chung-
dc.identifier.doi10.1097/DSS.0000000000002827-
dc.contributor.localIdA00520-
dc.contributor.localIdA01278-
dc.contributor.localIdA04583-
dc.contributor.localIdA05152-
dc.contributor.localIdA03582-
dc.contributor.localIdA01278-
dc.contributor.localIdA04583-
dc.contributor.localIdA05152-
dc.contributor.localIdA03582-
dc.relation.journalcodeJ00707-
dc.identifier.eissn1524-4725-
dc.identifier.pmid33481431-
dc.identifier.urlhttps://journals.lww.com/dermatologicsurgery/Fulltext/2021/02000/Slow_Mohs_Micrographic_Surgery_for_Acral_Melanoma.14.aspx-
dc.contributor.alternativeNameKim, Sang Kyum-
dc.contributor.affiliatedAuthor김상겸-
dc.contributor.affiliatedAuthor노미령-
dc.contributor.affiliatedAuthor서지명-
dc.contributor.affiliatedAuthor오영주-
dc.contributor.affiliatedAuthor정기양-
dc.contributor.affiliatedAuthor노미령-
dc.contributor.affiliatedAuthor서지명-
dc.contributor.affiliatedAuthor오영주-
dc.contributor.affiliatedAuthor정기양-
dc.citation.volume47-
dc.citation.number2-
dc.citation.startPagee42-
dc.citation.endPagee46-
dc.identifier.bibliographicCitationDERMATOLOGIC SURGERY, Vol.47(2) : e42-e46, 2021-02-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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