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Development of evidence-based consensus on critical issues in the management of patients with vitiligo: A modified Delphi study

Authors
 Jung Min Bae  ;  Ki-Heon Jeong  ;  Chong Won Choi  ;  Ji Hun Park  ;  Hee Jung Lee  ;  Hee Jung Kim  ;  Sang Hoon Lee  ;  Sang Ho Oh  ;  Jeonghyun Shin  ;  Hee Young Kang  ;  Weon Ju Lee  ;  Hyun Jeong Ju  ;  Dong Hyun Kim  ;  Sung Eun Chang  ;  Dong Youn Lee  ;  You Chan Kim  ;  Gwang Seong Choi  ;  Ki-Ho Kim  ;  Tae Heung Kim  ;  Seung Chul Lee  ;  Ai-Young Lee  ;  Seung-Kyung Hann  ;  Mu-Hyoung Lee  ;  Chul Jong Park 
Citation
 PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, Vol.37(1) : 3-11, 2021-01 
Journal Title
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE
ISSN
 0905-4383 
Issue Date
2021-01
Keywords
Delphi ; expert ; guideline ; recommendation ; surgery ; treatment ; vitiligo
Abstract
Background/purpose: Vitiligo remains a major challenge in dermatology. However, much of the treatment remains unclear, because little evidence is available. We sought to answer some critical questions pertaining to management of vitiligo patients.

Methods: A modified Delphi process among 31 vitiligo experts was conducted. A total of 12 clinical vitiligo treatment questions without clear answers were collected via a vote. To address each question, two members performed systematic literature reviews and prepared draft statements along with the levels of evidence and strength of recommendation. After reviewing the draft, all expressed their extent of agreement from 1 (strong disagreement) to 9 (strong agreement) for each item. The drafts were revised to reflect suggested comments. Discussion continued until all members agreed with the ultimate decision.

Results: The consensus process was completed after five rounds. We identified the best answers to 12 key questions, including issues on long-term phototherapy, systemic and topical corticosteroids, topical calcineurin inhibitors, immunosuppressants, excimer laser treatment, and surgical interventions.

Conclusion: This consensus would complement current guidelines and aid both physician and patient decision-making in the treatment of vitiligo.
Full Text
https://onlinelibrary.wiley.com/doi/10.1111/phpp.12598
DOI
10.1111/phpp.12598
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Sang Ho(오상호) ORCID logo https://orcid.org/0000-0002-4477-1400
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/184142
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