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Effect of Equal Ratio Ventilation on Respiratory Mechanics and Oxygenation During Volume-Controlled Ventilation in Pediatric Patients

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dc.contributor.author구본녀-
dc.contributor.author김은정-
dc.contributor.author윤혜진-
dc.contributor.author함성연-
dc.contributor.author김은정-
dc.contributor.author윤혜진-
dc.contributor.author함성연-
dc.date.accessioned2021-09-29T00:48:35Z-
dc.date.available2021-09-29T00:48:35Z-
dc.date.issued2021-06-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/184046-
dc.description.abstractPurpose: Children have few small alveoli, which reduce lung compliance; in contrast, their cartilaginous rib cage makes their chest wall highly compliant. This combination promotes lung collapse. Prolonged inspiratory to expiratory (I:E) ratio ventilation is used to optimize gas exchange and respiratory mechanics in surgery. However, the optimal ratio is unclear in children. We hypothesized that, compared to a 1:2 I:E ratio, a 1:1 I:E ratio would improve dynamic compliance and oxygenation, and affect the peak airway pressure in pediatric patients undergoing surgery. Materials and methods: Forty-eight patients aged ≤6 years who were scheduled to undergo surgery under general anesthesia with an arterial line were randomly allocated to receive 1:1 (group 1:1) or 1:2 (group 1:2) I:E ratio ventilation. Airway pressure, respiratory system compliance, and arterial blood gas analyses were compared between groups immediately after induction (T0), 30 min after induction (T1), 60 min after induction (T2), immediately after surgery (T3), and on arrival at the post-anesthesia care unit (T4). Results: Peak and plateau airway pressures were significantly lower in group 1:1 than in group 1:2 at T1 (p=0.044 and 0.048, respectively). The dynamic and static compliances were significantly higher in group 1:1 than in group 1:2 at T1 (p=0.044 and 0.045, respectively). However, the partial pressure of oxygen did not significantly differ between groups. Conclusion: Compared to a 1:2 I:E ratio, a 1:1 I:E ratio improved dynamic compliance and lowered the peak airway pressure without complications in pediatric patients. Nevertheless, our results do not support its use solely for improving oxygenation.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHBlood Gas Analysis-
dc.subject.MESHChild-
dc.subject.MESHHumans-
dc.subject.MESHLung-
dc.subject.MESHLung Compliance-
dc.subject.MESHPulmonary Gas Exchange-
dc.subject.MESHRespiration, Artificial*-
dc.subject.MESHRespiratory Mechanics*-
dc.titleEffect of Equal Ratio Ventilation on Respiratory Mechanics and Oxygenation During Volume-Controlled Ventilation in Pediatric Patients-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology and Pain Medicine (마취통증의학교실)-
dc.contributor.googleauthorHa Yeon Kim-
dc.contributor.googleauthorSung Yeon Ham-
dc.contributor.googleauthorEun Jung Kim-
dc.contributor.googleauthorHei Jin Yoon-
dc.contributor.googleauthorSeung Yeon Choi-
dc.contributor.googleauthorBon Nyeo Koo-
dc.identifier.doi10.3349/ymj.2021.62.6.503-
dc.contributor.localIdA00193-
dc.contributor.localIdA00816-
dc.contributor.localIdA05796-
dc.contributor.localIdA05192-
dc.contributor.localIdA00816-
dc.contributor.localIdA05796-
dc.contributor.localIdA05192-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid34027637-
dc.subject.keywordBlood gas analysis-
dc.subject.keywordexhalation-
dc.subject.keywordinhalation-
dc.subject.keywordpediatrics-
dc.subject.keywordpositive pressure breathing-
dc.subject.keywordrespiratory mechanics-
dc.contributor.alternativeNameKu, Bon Nyo-
dc.contributor.affiliatedAuthor구본녀-
dc.contributor.affiliatedAuthor김은정-
dc.contributor.affiliatedAuthor윤혜진-
dc.contributor.affiliatedAuthor함성연-
dc.contributor.affiliatedAuthor김은정-
dc.contributor.affiliatedAuthor윤혜진-
dc.contributor.affiliatedAuthor함성연-
dc.citation.volume62-
dc.citation.number6-
dc.citation.startPage503-
dc.citation.endPage509-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.62(6) : 503-509, 2021-06-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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