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Reversibility of Endoscopic Features after Treatment for Eosinophilic Esophagitis

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dc.contributor.author박준철-
dc.contributor.author박효진-
dc.contributor.author윤영훈-
dc.contributor.author박효진-
dc.contributor.author윤영훈-
dc.date.accessioned2021-09-29T00:45:09Z-
dc.date.available2021-09-29T00:45:09Z-
dc.date.issued2021-06-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/184018-
dc.description.abstractPurpose: The prevalence and incidence of eosinophilic esophagitis (EoE) are increasing worldwide. Despite increased understanding of inflammatory pathogenesis, changes in endoscopic features after treatment of EoE have not been clearly described. We aimed to investigate the reversibility of endoscopic features of EoE after treatment. Materials and methods: Out of 58 adult subjects who were diagnosed with EoE at the Yonsei University Health System from July 2006 to August 2019, we recruited 33 subjects (30 males; mean age: 42 years) whose pre-treatment and post-treatment endoscopic images were available. Endoscopic features included both inflammatory and fibrostenotic features. Exudate, edema, furrow, and crepe paper-like mucosa were classified as inflammatory features. Ring and stricture were classified as fibrostenotic features. We compared changes in endoscopic features after treatment for EoE. Results: After treatment, clinical symptoms improved in all patients. The following endoscopic features were observed before treatment: furrow (81.8%), edema (90.9%), exudate (42.4%), ring (27.3%), crepe paper-like mucosa (15.2%), and stricture (3.0%). Endoscopic remission was achieved in 21 patients (63.6%). Inflammatory features were reversible (72.7%, p<0.001), whereas fibrostenotic features were not (10%, p=0.160). Exudate had resolved in 92.9% of patients, edema in 70% and furrow in 88.9%. Ring and stricture persisted in almost all of the patients (9/10) who had these endoscopic features before treatment. Conclusion: We outlined the reversibility of endoscopic inflammatory features of EoE. Fibrostenotic features were irreversible after esophageal remodeling in patients with EoE. However, further validation studies with long-term follow-up are needed.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHEdema-
dc.subject.MESHEndoscopy-
dc.subject.MESHEosinophilic Esophagitis*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMucous Membrane-
dc.titleReversibility of Endoscopic Features after Treatment for Eosinophilic Esophagitis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorHong Jin Yoon-
dc.contributor.googleauthorYoung Hoon Youn-
dc.contributor.googleauthorJun Chul Park-
dc.contributor.googleauthorHyojin Park-
dc.identifier.doi10.3349/ymj.2021.62.6.487-
dc.contributor.localIdA01676-
dc.contributor.localIdA01774-
dc.contributor.localIdA02583-
dc.contributor.localIdA01774-
dc.contributor.localIdA02583-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid34027635-
dc.subject.keywordEsophagus-
dc.subject.keywordeosinophilia-
dc.subject.keywordeosinophilic esophagitis-
dc.contributor.alternativeNamePark, Jun Chul-
dc.contributor.affiliatedAuthor박준철-
dc.contributor.affiliatedAuthor박효진-
dc.contributor.affiliatedAuthor윤영훈-
dc.contributor.affiliatedAuthor박효진-
dc.contributor.affiliatedAuthor윤영훈-
dc.citation.volume62-
dc.citation.number6-
dc.citation.startPage487-
dc.citation.endPage493-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.62(6) : 487-493, 2021-06-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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