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Characteristics of community-acquired respiratory viruses infections except seasonal influenza in transplant recipients and non-transplant critically ill patients
DC Field | Value | Language |
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dc.contributor.author | 김명수 | - |
dc.contributor.author | 김순일 | - |
dc.contributor.author | 김유선 | - |
dc.contributor.author | 김진석 | - |
dc.contributor.author | 민유홍 | - |
dc.contributor.author | 송영구 | - |
dc.contributor.author | 이경화 | - |
dc.contributor.author | 정준원 | - |
dc.contributor.author | 조용근 | - |
dc.contributor.author | 최진섭 | - |
dc.contributor.author | 한상훈 | - |
dc.date.accessioned | 2021-09-29T00:44:42Z | - |
dc.date.available | 2021-09-29T00:44:42Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/184015 | - |
dc.description.abstract | Background/purpose: Transplant recipients are vulnerable to life-threatening community-acquired respiratory viruses (CA-RVs) infection (CA-RVI). Even if non-transplant critically ill patients in intensive care unit (ICU) have serious CA-RVI, comparison between these groups remains unclear. We aimed to evaluate clinical characteristics and mortality of CA-RVI except seasonal influenza A/B in transplant recipients and non-transplant critically ill patients in ICU. Methods: We collected 37,777 CA-RVs multiplex real-time reverse transcription-polymerase chain reaction test results of individuals aged ≥18 years from November 2012 to November 2017. The CA-RVs tests included adenovirus, coronavirus 229E/NL63/OC43, human bocavirus, human metapneumovirus, parainfluenza virus 1/2/3, rhinovirus, and respiratory syncytial virus A/B. Results: We found 286 CA-RVI cases, including 85 solid organ transplantation recipients (G1), 61 hematopoietic stem cell transplantation recipients (G2), and 140 non-transplant critically ill patients in ICU (G3), excluding those with repeated isolation within 30 days. Adenovirus positive rate and infection cases were most prominent in G2 (p < 0.001). The median time interval between transplantation and CA-RVI was 30 and 20 months in G1 and G2, respectively. All-cause in-hospital mortality was significantly higher in G3 than in G1 or G2 (51.4% vs. 28.2% or 39.3%, p = 0.002, respectively). The mechanical ventilation (MV) was the independent risk factor associated with all-cause in-hospital mortality in all three groups (hazard ratio, 3.37, 95% confidence interval, 2.04-5.56, p < 0.001). Conclusions: This study highlights the importance of CA-RVs diagnosis in transplant recipients even in long-term posttransplant period, and in non-transplant critically ill patients in ICU with MV. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Chinese | - |
dc.publisher | Elsevier for the Taiwan Society of Microbiology | - |
dc.relation.isPartOf | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Community-Acquired Infections / etiology* | - |
dc.subject.MESH | Community-Acquired Infections / mortality | - |
dc.subject.MESH | Community-Acquired Infections / virology | - |
dc.subject.MESH | Critical Illness | - |
dc.subject.MESH | Disease Susceptibility | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hematopoietic Stem Cell Transplantation / adverse effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunocompromised Host | - |
dc.subject.MESH | Immunosuppression / adverse effects | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Organ Transplantation / adverse effects | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Respiratory Tract Infections / etiology* | - |
dc.subject.MESH | Respiratory Tract Infections / mortality | - |
dc.subject.MESH | Respiratory Tract Infections / virology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Transplant Recipients* | - |
dc.title | Characteristics of community-acquired respiratory viruses infections except seasonal influenza in transplant recipients and non-transplant critically ill patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Kyoung Hwa Lee | - |
dc.contributor.googleauthor | Seul Gi Yoo | - |
dc.contributor.googleauthor | Yonggeun Cho | - |
dc.contributor.googleauthor | Da Eun Kwon | - |
dc.contributor.googleauthor | Yeonju La | - |
dc.contributor.googleauthor | Sang Hoon Han | - |
dc.contributor.googleauthor | Myoung Soo Kim | - |
dc.contributor.googleauthor | Jin Sub Choi | - |
dc.contributor.googleauthor | Soon Il Kim | - |
dc.contributor.googleauthor | Yu Seun Kim | - |
dc.contributor.googleauthor | Yoo Hong Min | - |
dc.contributor.googleauthor | June-Won Cheong | - |
dc.contributor.googleauthor | Jin Seok Kim | - |
dc.contributor.googleauthor | Yong Goo Song | - |
dc.identifier.doi | 10.1016/j.jmii.2019.05.007 | - |
dc.contributor.localId | A00424 | - |
dc.contributor.localId | A00649 | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A01017 | - |
dc.contributor.localId | A01407 | - |
dc.contributor.localId | A02037 | - |
dc.contributor.localId | A04620 | - |
dc.contributor.localId | A03729 | - |
dc.contributor.localId | A03864 | - |
dc.contributor.localId | A04199 | - |
dc.contributor.localId | A04286 | - |
dc.relation.journalcode | J01595 | - |
dc.identifier.eissn | 1995-9133 | - |
dc.identifier.pmid | 31262511 | - |
dc.subject.keyword | Community-acquired respiratory viruses | - |
dc.subject.keyword | Critically ill patients | - |
dc.subject.keyword | Hematopoietic stem cell transplantation | - |
dc.subject.keyword | Mortality | - |
dc.subject.keyword | Solid organ transplantation | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.affiliatedAuthor | 김명수 | - |
dc.contributor.affiliatedAuthor | 김순일 | - |
dc.contributor.affiliatedAuthor | 김유선 | - |
dc.contributor.affiliatedAuthor | 김진석 | - |
dc.contributor.affiliatedAuthor | 민유홍 | - |
dc.contributor.affiliatedAuthor | 송영구 | - |
dc.contributor.affiliatedAuthor | 이경화 | - |
dc.contributor.affiliatedAuthor | 정준원 | - |
dc.contributor.affiliatedAuthor | 조용근 | - |
dc.contributor.affiliatedAuthor | 최진섭 | - |
dc.contributor.affiliatedAuthor | 한상훈 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 253 | - |
dc.citation.endPage | 260 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, Vol.54(2) : 253-260, 2021-04 | - |
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