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Effect of alcohol consumption on the risk of adverse events in atrial fibrillation: from the COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation (CODE-AF) registry

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dc.contributor.author김태훈-
dc.contributor.author엄재선-
dc.contributor.author유희태-
dc.contributor.author정보영-
dc.date.accessioned2021-09-29T00:41:20Z-
dc.date.available2021-09-29T00:41:20Z-
dc.date.issued2021-04-
dc.identifier.issn1099-5129-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/183987-
dc.description.abstractAims: The aim of this study is to determine the relationship between alcohol consumption and atrial fibrillation (AF)-related adverse events in the AF population. Methods and results: A total of 9411 patients with nonvalvular AF in a prospective observational registry were categorized into four groups according to the amount of alcohol consumption-abstainer-rare, light (<100 g/week), moderate (100-200 g/week), and heavy (≥200 g/week). Data on adverse events (ischaemic stroke, transient ischaemic attack, systemic embolic event, or AF hospitalization including for AF rate or rhythm control and heart failure management) were collected for 17.4 ± 7.3 months. A Cox proportional hazard models was performed to calculate hazard ratios (HRs), and propensity score matching was conducted to validate the results. The heavy alcohol consumption group showed an increased risk of composite adverse outcomes [adjusted hazard ratio (aHR) 1.32, 95% confidence interval (CI) 1.06-1.66] compared with the reference group (abstainer-rare group). However, no significant increased risk for adverse outcomes was observed in the light (aHR 0.88, 95% CI 0.68-1.13) and moderate (aHR 0.91, 95% CI 0.63-1.33) groups. In subgroup analyses, adverse effect of heavy alcohol consumption was significant, especially among patients with low CHA2DS2-VASc score, without hypertension, and in whom β-blocker were not prescribed. Conclusion: Our findings suggest that heavy alcohol consumption increases the risk of adverse events in patients with AF, whereas light or moderate alcohol consumption does not.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherOxford University Press-
dc.relation.isPartOfEUROPACE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleEffect of alcohol consumption on the risk of adverse events in atrial fibrillation: from the COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation (CODE-AF) registry-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorChewan Lim-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorHee Tae Yu-
dc.contributor.googleauthorSo-Ryoung Lee-
dc.contributor.googleauthorMyung-Jin Cha-
dc.contributor.googleauthorJung-Myung Lee-
dc.contributor.googleauthorJunbeom Park-
dc.contributor.googleauthorJin-Kyu Park-
dc.contributor.googleauthorKi-Woon Kang-
dc.contributor.googleauthorJaemin Shim-
dc.contributor.googleauthorJae-Sun Uhm-
dc.contributor.googleauthorJun Kim-
dc.contributor.googleauthorHyung Wook Park-
dc.contributor.googleauthorEue-Keun Choi-
dc.contributor.googleauthorJin-Bae Kim-
dc.contributor.googleauthorYoung Soo Lee-
dc.contributor.googleauthorBoyoung Joung-
dc.identifier.doi10.1093/europace/euaa340-
dc.contributor.localIdA01085-
dc.contributor.localIdA02337-
dc.contributor.localIdA02535-
dc.contributor.localIdA03609-
dc.relation.journalcodeJ00801-
dc.identifier.eissn1532-2092-
dc.identifier.pmid33227134-
dc.identifier.urlhttps://academic.oup.com/europace/article/23/4/548/5998957-
dc.subject.keywordAlcohol consumption-
dc.subject.keywordAtrial fibrillation-
dc.subject.keywordHeavy drinking-
dc.subject.keywordHospitalization-
dc.subject.keywordRegistry-
dc.subject.keywordStroke-
dc.contributor.alternativeNameKim, Tae-Hoon-
dc.contributor.affiliatedAuthor김태훈-
dc.contributor.affiliatedAuthor엄재선-
dc.contributor.affiliatedAuthor유희태-
dc.contributor.affiliatedAuthor정보영-
dc.citation.volume23-
dc.citation.number4-
dc.citation.startPage548-
dc.citation.endPage556-
dc.identifier.bibliographicCitationEUROPACE, Vol.23(4) : 548-556, 2021-04-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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