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Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea
DC Field | Value | Language |
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dc.contributor.author | 이병완 | - |
dc.date.accessioned | 2021-09-29T00:35:05Z | - |
dc.date.available | 2021-09-29T00:35:05Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 2093-596X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183931 | - |
dc.description.abstract | Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea. Methods: We extracted claims data for patients diagnosed with COVID-19 from the National Health Insurance Service database in Korea from January 20, 2020 to March 31, 2020. We followed up this cohort until death from COVID-19 or discharge from hospital. Results: A total of 5,473 patients diagnosed with COVID-19 were analyzed, including 495 with type 2 diabetes and 4,978 without diabetes. Patients with type 2 diabetes were more likely to be treated in the intensive care unit (ICU) (P<0.0001). The incidence of inhospital mortality was higher in patients with type 2 diabetes (P<0.0001). After adjustment for age, sex, insurance status, and comorbidities, odds of ICU admission (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI], 1.02 to 2.49; P=0.0416) and in-hospital mortality (adjusted OR, 1.90; 95% CI, 1.13 to 3.21; P=0.0161) among patients with COVID-19 infection were significantly higher in those with type 2 diabetes. However, there was no significant difference between patients with and without type 2 diabetes in ventilator, oxygen therapy, antibiotics, antiviral drugs, antipyretics, and the incidence of pneumonia after adjustment. Conclusion: COVID-19 positive patients with type 2 diabetes had poorer clinical outcomes with higher risk of ICU admission and in-hospital mortality than those without diabetes. Therefore, medical providers need to consider this more serious clinical course when planning and delivering care to type 2 diabetes patients with COVID-19 infection. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Endocrine Society | - |
dc.relation.isPartOf | Endocrinology and Metabolism(대한내분비학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | COVID-19 / complications | - |
dc.subject.MESH | COVID-19 / diagnosis* | - |
dc.subject.MESH | COVID-19 / epidemiology* | - |
dc.subject.MESH | COVID-19 / mortality | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Comorbidity | - |
dc.subject.MESH | Diabetes Mellitus, Type 2 / complications | - |
dc.subject.MESH | Diabetes Mellitus, Type 2 / diagnosis* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2 / epidemiology* | - |
dc.subject.MESH | Diabetes Mellitus, Type 2 / mortality | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Hospital Mortality | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Intensive Care Units | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pandemics | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | SARS-CoV-2 / physiology | - |
dc.subject.MESH | Young Adult | - |
dc.title | Clinical Outcomes of COVID-19 Patients with Type 2 Diabetes: A Population-Based Study in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Ji Hong You | - |
dc.contributor.googleauthor | Sang Ah Lee | - |
dc.contributor.googleauthor | Sung-Youn Chun | - |
dc.contributor.googleauthor | Sun Ok Song | - |
dc.contributor.googleauthor | Byung-Wan Lee | - |
dc.contributor.googleauthor | Dae Jung Kim | - |
dc.contributor.googleauthor | Edward J Boyko | - |
dc.identifier.doi | 10.3803/EnM.2020.787 | - |
dc.contributor.localId | A02796 | - |
dc.relation.journalcode | J00773 | - |
dc.identifier.eissn | 2093-5978 | - |
dc.identifier.pmid | 33297603 | - |
dc.subject.keyword | COVID-19 | - |
dc.subject.keyword | Diabetes mellitus, type 2 | - |
dc.subject.keyword | Epidemiology | - |
dc.subject.keyword | Incidence | - |
dc.subject.keyword | Mortality | - |
dc.contributor.alternativeName | Lee, Byung Wan | - |
dc.contributor.affiliatedAuthor | 이병완 | - |
dc.citation.volume | 35 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 901 | - |
dc.citation.endPage | 908 | - |
dc.identifier.bibliographicCitation | Endocrinology and Metabolism (대한내분비학회지), Vol.35(4) : 901-908, 2020-12 | - |
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