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Long-term compensation of renal function after donor nephrectomy
DC Field | Value | Language |
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dc.contributor.author | 김명수 | - |
dc.contributor.author | 김수진 | - |
dc.contributor.author | 김순일 | - |
dc.contributor.author | 김유선 | - |
dc.contributor.author | 이재근 | - |
dc.contributor.author | 이주한 | - |
dc.contributor.author | 주동진 | - |
dc.contributor.author | 허규하 | - |
dc.date.accessioned | 2021-09-29T00:23:37Z | - |
dc.date.available | 2021-09-29T00:23:37Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 1298-1711 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183806 | - |
dc.description.abstract | Background: Living donors are the major source of kidneys in countries with a shortage of deceased donors. Kidney donation after careful donor selection is generally accepted as a safe procedure, but the physiologic consequences after donor nephrectomy are not fully verified. In this study we retrospectively reviewed the renal function of the residual kidney in living donors. Methods: Post-nephrectomy laboratory data of 1,175 living donors (60.7%) from 1,933 living donors who received uninephrectomy from January 1999 to December 2017 at Yonsei University, Severance Hospital, Korea were retrospectively collected. Post-nephrectomy renal function was monitored by the relative ratio of estimated glomerular filtration rate (e-GFR; pre-nephrectomy e-GFR ratio vs. post-nephrectomy e-GFR) that was calculated by the Modification of Diet in Renal Disease formula. Results: During 36.3±37.6 months of mean follow-up, two cases (0.17%, 2/1,175) of renal failure developed. The mean e-GFR decreased to 64.3±14.2 mL/min/1.73 m2 immediately after nephrectomy from 99.2±19.9 mL/min/1.73 m2 of the pre-nephrectomy e-GFR. Early decrement of e-GFR was prominent in male and obese donors (body mass index >25 kg/m2, P<0.05). The e-GFR ratio increased according to post-nephrectomy duration, and the mean increment degree of e-GFR ratio after nephrectomy calculated by linear regression analysis was 1.94% per year. Unlike the early decrement of e-GFR ratio after nephrectomy, donor factors such as degree of obesity and donor sex did not affect the late increment of e-GFR ratio after nephrectomy (P>0.05). Conclusions: Our data showed that long-term compensation of the renal function after nephrectomy occurs independently of preoperative donor characteristics. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Journal of the Korean Society for Transplantation | - |
dc.publisher | Journal of the Korean Society for Transplantation | - |
dc.relation.isPartOf | Journal of the Korean Society for Transplantation | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Long-term compensation of renal function after donor nephrectomy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Yong Pyo Lee | - |
dc.contributor.googleauthor | Soo Jin Kim | - |
dc.contributor.googleauthor | Juhan Lee | - |
dc.contributor.googleauthor | Jae Geun Lee | - |
dc.contributor.googleauthor | Kyu Ha Huh | - |
dc.contributor.googleauthor | Dong Jin Joo | - |
dc.contributor.googleauthor | Soon Il Kim | - |
dc.contributor.googleauthor | Yu Seun Kim | - |
dc.contributor.googleauthor | Myoung Soo Kim | - |
dc.identifier.doi | 10.4285/kjt.2020.34.2.84 | - |
dc.contributor.localId | A00424 | - |
dc.contributor.localId | A00636 | - |
dc.contributor.localId | A00649 | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A03068 | - |
dc.contributor.localId | A03163 | - |
dc.contributor.localId | A03948 | - |
dc.contributor.localId | A04344 | - |
dc.relation.journalcode | J01858 | - |
dc.identifier.eissn | 2508-2604 | - |
dc.subject.keyword | Glomerular filtration rate | - |
dc.subject.keyword | Nephrectomy | - |
dc.subject.keyword | Living donors | - |
dc.subject.keyword | Kidney transplantation | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.affiliatedAuthor | 김명수 | - |
dc.contributor.affiliatedAuthor | 김수진 | - |
dc.contributor.affiliatedAuthor | 김순일 | - |
dc.contributor.affiliatedAuthor | 김유선 | - |
dc.contributor.affiliatedAuthor | 이재근 | - |
dc.contributor.affiliatedAuthor | 이주한 | - |
dc.contributor.affiliatedAuthor | 주동진 | - |
dc.contributor.affiliatedAuthor | 허규하 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 84 | - |
dc.citation.endPage | 91 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Society for Transplantation, Vol.34(2) : 84-91, 2020-06 | - |
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