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Efficacy of Rhino-Protect ointment after endoscopic sinus surgery: a prospective, randomized, multicenter study
DC Field | Value | Language |
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dc.contributor.author | 김창훈 | - |
dc.date.accessioned | 2021-09-29T00:22:46Z | - |
dc.date.available | 2021-09-29T00:22:46Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 0937-4477 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183798 | - |
dc.description.abstract | Objective: Blocking airflow into the sinonasal cavity after surgery may help to keep the cavity moist and thus decrease postoperative crusting. Here we investigated the efficacy of Rhino-Protect ointment following endoscopic sinus surgery (ESS). Subjects and methods: A total of 93 patients with chronic rhinosinusitis who underwent identical ESS were enrolled. After surgery, all patients were instructed to perform nasal saline irrigation and deliver a nasal spray to each nostril, then to apply Rhino-Protect ointment to one nostril only; the other nostril served as a control. Subjective symptoms, postoperative Lund-Kennedy (LK) endoscopic scores, and adverse reactions 14 and 28 days after treatment were evaluated. Results: The Rhino-Protect ointment significantly reduced pain (p = 0.015 at 28 days), dryness (p = 0.009 at 14 days and p = 0.045 at 28 days), and crusting (p = 0.047 at 14 days), and was associated with significantly lower LK scores 14 and 28 days after treatment (p = 0.037 and p = 0.007, respectively). Statistically significant differences were noted in the LK edema subscore at 14 days (p = 0.043) and in LK crusting subscores at 14 and 28 days (p = 0.005 and p = 0.006, respectively). No patient reported any serious adverse event associated with Rhino-Protect use. Conclusion: Applying Rhino-Protect after ESS significantly reduced the formation of edema and crusts, leading to improving the patients' discomfort for pain, dryness, and crust. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer International | - |
dc.relation.isPartOf | EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Chronic Disease | - |
dc.subject.MESH | Endoscopy / adverse effects* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Ointments / therapeutic use* | - |
dc.subject.MESH | Otorhinolaryngologic Surgical Procedures / adverse effects* | - |
dc.subject.MESH | Paranasal Sinuses / surgery* | - |
dc.subject.MESH | Postoperative Complications / prevention & control | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Rhinitis / drug therapy | - |
dc.subject.MESH | Rhinitis / surgery | - |
dc.subject.MESH | Sinusitis / surgery* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Efficacy of Rhino-Protect ointment after endoscopic sinus surgery: a prospective, randomized, multicenter study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학교실) | - |
dc.contributor.googleauthor | Kyu-Sup Cho | - |
dc.contributor.googleauthor | Soo Whan Kim | - |
dc.contributor.googleauthor | Jin Kook Kim | - |
dc.contributor.googleauthor | Chang-Hoon Kim | - |
dc.identifier.doi | 10.1007/s00405-020-06265-4 | - |
dc.contributor.localId | A01050 | - |
dc.relation.journalcode | J00802 | - |
dc.identifier.eissn | 1434-4726 | - |
dc.identifier.pmid | 32757038 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s00405-020-06265-4 | - |
dc.subject.keyword | Dr. Theiss Rhino-Protect® PRS | - |
dc.subject.keyword | Endoscopic sinus surgery | - |
dc.subject.keyword | Nose | - |
dc.subject.keyword | Postoperative care | - |
dc.subject.keyword | Wound healing | - |
dc.contributor.alternativeName | Kim, Chang Hoon | - |
dc.contributor.affiliatedAuthor | 김창훈 | - |
dc.citation.volume | 278 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 109 | - |
dc.citation.endPage | 115 | - |
dc.identifier.bibliographicCitation | EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, Vol.278(1) : 109-115, 2021-01 | - |
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