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Increased serum interleukin-10 level in Kawasaki disease
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.date.accessioned | 2021-09-28T08:33:20Z | - |
dc.date.available | 2021-09-28T08:33:20Z | - |
dc.date.issued | 1996-04 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183712 | - |
dc.description.abstract | Serum IL-10 level in Kawasaki disease(KD) was tested. In the KD patients' sera during the acute phase, the levels of IL-10 were markedly elevated (122.0 ± 39.1 pg/ml) compared to 3.7 ± 1.7 pg/ml in the control subjects (p< 0.001). The serum IL-10 levels remained elevated in the subacute phase (16. 7 ± 9.7 pg/ml, p< 0.001) and were restored to the normal levels(7.9 ± 3.9 pg/ml) during the convalescent phase. In the patients with acute febrile disease, the serum IL-10 level increased significantly (34.4 ± 14.1 pg/ml, p< 0.001) compared to that of the age-matched control subjects, but were not as high as in acute phase of KD(p< 0.005). This increase in serum IL-10 levels in KD may contribute to the up-regulation of humoral immunity and to the down-regulation of acute inflammation due to an increase in proinflammatory cytokines. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Interleukin-10 / blood* | - |
dc.subject.MESH | Interleukin-12 / blood | - |
dc.subject.MESH | Interleukin-4 / blood | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Mucocutaneous Lymph Node Syndrome / blood | - |
dc.subject.MESH | Mucocutaneous Lymph Node Syndrome / immunology* | - |
dc.title | Increased serum interleukin-10 level in Kawasaki disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Dong Soo Kim | - |
dc.contributor.googleauthor | Hong Kyu Lee | - |
dc.contributor.googleauthor | Geun Woong Noh | - |
dc.contributor.googleauthor | Soon Il Lee | - |
dc.contributor.googleauthor | Ki Young Lee | - |
dc.identifier.doi | 10.3349/ymj.1996.37.2.125 | - |
dc.contributor.localId | A00405 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 8711935 | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.affiliatedAuthor | 김동수 | - |
dc.citation.volume | 37 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 125 | - |
dc.citation.endPage | 130 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.37(2) : 125-130, 1996-04 | - |
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