요와 농검체에서의 vancomycin 내성 장구균 분리 2예

Abstract

Vancomycin-resistant Enterococcus faecalis and E. faecium were isolated from urine and decubitus ulcer discharge, respectively, from a 65-year-old woman. Prior to the transfer to this hospital in December, 1995, she had been admitted to the Chicago Rehabilitation Center in the U.S. for the treatment of olivopontocerebellar atrophy, quadriplegia, and neurogenic bladder. She was also treated with multiple antimicrobials including vancomycin for pneumonia at intensive care unit, which suggested that she acquired the organisms in the U.S. The minimal inhibitory concentrations of vancomycin and teicoplanin against the isolates were: E. faecalis 256μg/mL and 0.5μg/mL; E. faecium 32μg/mL and 0.5μg/mL, respectively. The susceptibility patterns suggest the isolates are vanB type. Although other species of vancomycin-resistant Enterococcus spp. were reported previously in Korea, these isolates may be the first vancomycin-resistant E. faecalis and E. faecium from clinical specimens.