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The affinity of allergen specific IgE and the competition between IgE and IgG for the allergen in Amb a V sensitive individuals
DC Field | Value | Language |
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dc.contributor.author | 김규언 | - |
dc.date.accessioned | 2021-09-28T08:07:10Z | - |
dc.date.available | 2021-09-28T08:07:10Z | - |
dc.date.issued | 1996-07 | - |
dc.identifier.issn | 0161-5890 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183426 | - |
dc.description.abstract | We have calibrated a solid state RAST assay with affinity purified allergen-specific IgE. We then utilized the calibrated assay to measure the average affinity of individual IgE-containing sera in terms of the average association constant 〈K〉 for purified allergen Amb a V. The binding data yielded linear reciprocal plots indicating that the range of affinities of the responding clones was narrow. The range of the average association constant for the IgE-Amb a V complex was 0.9–26 × 1010 M−1. The average affinity of the corresponding IgG response in the same individual, estimated by inhibition studies of IgE binding, was 107 M−1 in one case and lower than 106 M−1 in all the other cases. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Pergamon Press | - |
dc.relation.isPartOf | MOLECULAR IMMUNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Allergens / immunology* | - |
dc.subject.MESH | Antibody Specificity | - |
dc.subject.MESH | Antigens, Plant | - |
dc.subject.MESH | Binding, Competitive | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoglobulin E / immunology* | - |
dc.subject.MESH | Immunoglobulin G / immunology* | - |
dc.subject.MESH | Kinetics | - |
dc.subject.MESH | Mathematics | - |
dc.subject.MESH | Plant Proteins / immunology* | - |
dc.subject.MESH | Pollen / immunology* | - |
dc.subject.MESH | Radioallergosorbent Test | - |
dc.subject.MESH | Reference Values | - |
dc.title | The affinity of allergen specific IgE and the competition between IgE and IgG for the allergen in Amb a V sensitive individuals | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Kyu-Earn Kim | - |
dc.contributor.googleauthor | Andreas Rosenberg | - |
dc.contributor.googleauthor | Sean Roberts | - |
dc.contributor.googleauthor | Malcolm N. Blumenthal | - |
dc.identifier.doi | 10.1016/0161-5890(96)84613-X | - |
dc.contributor.localId | A00327 | - |
dc.relation.journalcode | J02259 | - |
dc.identifier.eissn | 1872-9142 | - |
dc.identifier.pmid | 8845019 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/016158909684613X | - |
dc.contributor.alternativeName | Kim, Kyu Earn | - |
dc.contributor.affiliatedAuthor | 김규언 | - |
dc.citation.volume | 33 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 873 | - |
dc.citation.endPage | 880 | - |
dc.identifier.bibliographicCitation | MOLECULAR IMMUNOLOGY, Vol.33(10) : 873-880, 1996-07 | - |
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