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R1R1(DCE/DEc) 환자에서 항-E항체와 항-C 항체의 동시 감작에 관한 고찰
DC Field | Value | Language |
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dc.contributor.author | 김현옥 | - |
dc.date.accessioned | 2021-09-28T08:03:33Z | - |
dc.date.available | 2021-09-28T08:03:33Z | - |
dc.date.issued | 1996-07 | - |
dc.identifier.issn | 1226-9336 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183384 | - |
dc.description.abstract | Anti-E and anti-c is one of the clinical significant irregular antibodies developing a delayed hemolytic transfusion reaction and hemolytic disease of the newborn. Since anti-c occurs frequently with anti-E in immunized people whose cells are E-and c-, it has been recommended to select blood of the patient큦 own R1 phenotype for transfusion, even when the presence of anti-c cannot be demonstrated in his/her serum. To determine the utility of this approach, we reviewed the blood bank laboratory records of patients identified anti-E and anti-c in his/her serum in Severance hospital over a 12 year period (1985~1996). During the 12-year period of study, 53 patients were identified with anti-E and/er anti-c; 30(56.6%) patients had anti-E alone, 6(11.3%) had anti-c, and 17(32.1%) had both. Thirty eight of forty two patients whose Rh-hr phenotypes were tested were R1R1. Of these 38 R1R1 patients, 16 patients (42.1%) presented with anti-c concomitant with anti-E. Our study showed that the incidence of anti-c in R1R1 patients with anti-E is similar to that of studies reported in Caucasian groups. We highly suggest the transfusion protocol of prophylactic use of c negative blood for R1R1 patients with anti-E. Furthermore, because antic may be present in concentrations too low to be detected, the enzyme technique is recommended in parallel with standard serologic methods for the identification of irregular antibodies. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한수혈학회 | - |
dc.relation.isPartOf | Korean Journal of Blood Transfusion(대한수혈학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | R1R1(DCE/DEc) 환자에서 항-E항체와 항-C 항체의 동시 감작에 관한 고찰 | - |
dc.title.alternative | The alloimmunization rate of anti-c concurrent with anti-E in R1R1 patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 안효준 | - |
dc.contributor.googleauthor | 엄용빈 | - |
dc.contributor.googleauthor | 이정신 | - |
dc.contributor.googleauthor | 최민자 | - |
dc.contributor.googleauthor | 김현옥 | - |
dc.contributor.localId | A01122 | - |
dc.relation.journalcode | J01970 | - |
dc.contributor.alternativeName | Kim, Hyun Ok | - |
dc.contributor.affiliatedAuthor | 김현옥 | - |
dc.citation.volume | 7 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 181 | - |
dc.citation.endPage | 186 | - |
dc.identifier.bibliographicCitation | Korean Journal of Blood Transfusion (대한수혈학회지), Vol.7(2) : 181-186, 1996-07 | - |
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