Cited 0 times in
초기소견으로 미세혈관병성 용혈성 빈혈상을 보인 골수전이성 악성흑색종 1례
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 민유홍 | - |
dc.contributor.author | 양우익 | - |
dc.date.accessioned | 2021-09-28T07:59:56Z | - |
dc.date.available | 2021-09-28T07:59:56Z | - |
dc.date.issued | 1996-12 | - |
dc.identifier.issn | 1225-0546 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183337 | - |
dc.description.abstract | The incidence and mortality rate of malignant melanoma has been increasing steadily over the past decade. The most common occurrence of marrow metastases in nonhematologic malignancies is in patients with carcinomas arising in the prostate, breast, lung and neuroblastoma but extremely rare in malignant melanoma. We report a rare case with presentation of simultaneous bone marrow metastatic malignant melanoma, microangiopathic hemolytic anemia and inguinal lymphadenopathy. A 59 years old female was admitted to hospital due to febrile and chilling sense for one month. On past history, a superficial skin lesion had been resected one year ago from the skin on right sole. On admission she had a 3 H 3cm sized well circumscribed right inguinal lymph node without any other lymphadenopathy. The hemogram revealed a hemoglobin of 9.6g/dL, leukocyte count of 22.8H 109/L, and platelet count of 95× 109/L. Studies for evaluation of primary cancer origin including chest, abdomen CT scanning, upper gastrointestinal series, colon barium enema, and radionuclide bone scan were normal except metastatic pulmonary nodule. Peripheral blood smear showed microspherocytes, fragmented RBCs, nucleated RBCs and myelocytes. Bone marrow aspiration and biopsy showed diffuse infiltration of marrow space by spindle shaped dysplastic cells having brown cytoplasmic pigment. These cells were stained positively for S 100 protein and HMB45 monoclonal antibody, negative for cytokeratin and desmin. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | Korean Society of Hematology | - |
dc.relation.isPartOf | Korean Journal of Hematology(대한혈액학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 초기소견으로 미세혈관병성 용혈성 빈혈상을 보인 골수전이성 악성흑색종 1례 | - |
dc.title.alternative | A Case of Bone Marrow Metastatic Malignant Melanoma Presenting Microangiopathic Hemolytic Anemia As Initial Clinical Findings | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 서형찬 | - |
dc.contributor.googleauthor | 민유홍 | - |
dc.contributor.googleauthor | 강웅철 | - |
dc.contributor.googleauthor | 이석 | - |
dc.contributor.googleauthor | 정소영 | - |
dc.contributor.googleauthor | 한지숙 | - |
dc.contributor.googleauthor | 고윤웅 | - |
dc.contributor.googleauthor | 양우익 | - |
dc.contributor.localId | A01407 | - |
dc.contributor.localId | A02300 | - |
dc.relation.journalcode | J02034 | - |
dc.subject.keyword | Malignant melanoma | - |
dc.subject.keyword | Bone marrow metastasis | - |
dc.subject.keyword | Microangiopathic hemolytic | - |
dc.contributor.alternativeName | Min, Yoo Hong | - |
dc.contributor.affiliatedAuthor | 민유홍 | - |
dc.contributor.affiliatedAuthor | 양우익 | - |
dc.citation.volume | 31 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 457 | - |
dc.citation.endPage | 464 | - |
dc.identifier.bibliographicCitation | Korean Journal of Hematology (대한혈액학회지), Vol.31(3) : 457-464, 1996-12 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.