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전립선 특이 항원 측정을 통한 전립선 조직유형의 추정

Other Titles
 The Relationship of Cellular Composition of Benign Prostatic Hyperplasia and Prostate-Specific Antigen(PSA) Levels 
Authors
 정병하  ;  이동현  ;  홍성준 
Citation
 Korean Journal of Urology (대한비뇨기과학회지), Vol.37(10) : 1093-1096, 1996-10 
Journal Title
KOREAN JOURNAL OF UROLOGY(대한비뇨기과학회지)
ISSN
 0494-4747 
Issue Date
1996-10
Keywords
Prostate Specific Antigen ; Benign Prostatic Hyperplasia ; Tissue composition
Abstract
The relationship between the serum values of prostate-specific antigen (PSA) and the histologic composition of benign prostatic hyperplasia (BPH) was investigated in 32 symptomatic BPH patients undergoing transurethral resection of the prostate. We evaluated the free and total PSA concentrations by ACS-PSA2 (Ciba-Corning) assay. The stereological analysis was made by computer aided-area densitometry using H & E stained slides to quantify stromal and glandular areas in the resected prostate tissue. The total PSA concentration versus percentage of glandular area (%G) and stromal-glandular ratio (SGR) correlated significantly (p<0.05 for both) whereas the free PSA concentration and free/total PSA ratio did not (p>0.05 for both). These data suggest that total PSA is directly correlated with the histologic composition of the prostate in men with BPH, however, the proportion of free to total PSA was not informative to predict the histology. Thus, pretreatment evaluation of total PSA would be useful as part of an evaluation method of BPH for medical therapy
Files in This Item:
T199601301.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Chung, Byung Ha(정병하) ORCID logo https://orcid.org/0000-0001-9817-3660
Hong, Sung Joon(홍성준) ORCID logo https://orcid.org/0000-0001-9869-065X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/183300
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