Ductal carcinoma in situ ; Breast conservation surgery
Abstract
In order to evaluate the effects of breast conservation surgery on ductal carcinoma in situ(DCIS) on locoregional recurrence, distant metastasis, morbidity and mortality, a randomized, prospective, clinical study of 46 patients with DCIS was performed. Three hundred seventy one patients with breast cancer were admitted at Yongdong Severance Hospital from Apr. 1991 to Mar. 1995. Among these, 46(14.5%) patients with DCIS were analyzed.. Of 46 patients, 8(17.4%), 26(56.5%) and 12(26.0%) patients had undergone modified radical mastectomy, total mastectomy or breast conservation surgery, respectively. All 12 patients who received breast conservation surgery had lesions less than 2cm. Among these, 6 were comedo type and the other were non-comedo type histologically. In the 6 non-comedo type patients, postoperative radiation therapy was not performed. During the follow-up period(minimum 7 months, maximum 53 months, average 20.4 months), locoregional recurrence, distant metastasis and overall survival were not statistically different between total mastectomy and the breast conservation surgery group. In this study, we conclude that "Breast Conservation Surgery" is a good alternative surgical treatment modality for ductal carcinoma in situ of the breast. However, longer follow-up periods will be necessary in order to reach more general conclusion.