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Overexpression of c-ErbB-2 Protein in Gastric Cancer by Immunohistochemical Stain
DC Field | Value | Language |
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dc.contributor.author | 김주항 | - |
dc.contributor.author | 노재경 | - |
dc.contributor.author | 라선영 | - |
dc.contributor.author | 정현철 | - |
dc.contributor.author | 조재용 | - |
dc.date.accessioned | 2021-09-28T07:40:27Z | - |
dc.date.available | 2021-09-28T07:40:27Z | - |
dc.date.issued | 1996-05 | - |
dc.identifier.issn | 0030-2414 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/183095 | - |
dc.description.abstract | An immunohistochemical stain to the c-ErbB-2 protein was performed in 225 paraffin-embedded tissue blocks from patients with locally advanced gastric cancer who underwent curative resection. The overexpression of the c-ErbB-2 protein was observed in 27.4% of the patients. The c-ErbB-2 positivity showed a statistically significant correlation with nodal status and stage. The patients with an overexpression of the c-ErbB-2 protein had a tendency to a shorter survival than those without, but it was not statistically significant (p = 0.08). The 5-year survival rate after surgery was 54% in the negative staining group to the c-ErbB-2 protein and 49% in the positive staining group. This suggests that the c-ErbB-2 protein has a possible role in lymph node metastasis. Therefore overexpression of the c-ErbB-2 protein is a useful indicator of disease progression in gastric carcinoma patients who received curative surgery. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Karger | - |
dc.relation.isPartOf | ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunohistochemistry | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Receptor, ErbB-2 / analysis* | - |
dc.subject.MESH | Stomach Neoplasms / chemistry* | - |
dc.subject.MESH | Stomach Neoplasms / pathology | - |
dc.subject.MESH | Stomach Neoplasms / surgery | - |
dc.subject.MESH | Survival Analysis | - |
dc.title | Overexpression of c-ErbB-2 Protein in Gastric Cancer by Immunohistochemical Stain | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Lee H.R. | - |
dc.contributor.googleauthor | Kim J.-H. | - |
dc.contributor.googleauthor | Uhm H.D. | - |
dc.contributor.googleauthor | Ahn J.B. | - |
dc.contributor.googleauthor | Rha S.Y. | - |
dc.contributor.googleauthor | Cho J.Y. | - |
dc.contributor.googleauthor | Lee J.I. | - |
dc.contributor.googleauthor | Lee K.H. | - |
dc.contributor.googleauthor | Chung H.C. | - |
dc.contributor.googleauthor | Roh J.K. | - |
dc.contributor.googleauthor | Min J.S. | - |
dc.contributor.googleauthor | Lee K.S. | - |
dc.contributor.googleauthor | Shin D.H. | - |
dc.contributor.googleauthor | Kim B.S. | - |
dc.contributor.googleauthor | Kim B.S. | - |
dc.contributor.googleauthor | Hong S.W. | - |
dc.contributor.googleauthor | Choi J.-H. | - |
dc.identifier.doi | 10.1159/000227559 | - |
dc.contributor.localId | A00945 | - |
dc.contributor.localId | A01290 | - |
dc.contributor.localId | A01316 | - |
dc.contributor.localId | A03773 | - |
dc.contributor.localId | A03899 | - |
dc.relation.journalcode | J02416 | - |
dc.identifier.eissn | 1423-0232 | - |
dc.identifier.pmid | 8643220 | - |
dc.identifier.url | http://www.karger.com/Article/FullText/227559 | - |
dc.contributor.alternativeName | Kim, Joo Hang | - |
dc.contributor.affiliatedAuthor | 김주항 | - |
dc.contributor.affiliatedAuthor | 노재경 | - |
dc.contributor.affiliatedAuthor | 라선영 | - |
dc.contributor.affiliatedAuthor | 정현철 | - |
dc.contributor.affiliatedAuthor | 조재용 | - |
dc.citation.volume | 53 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 192 | - |
dc.citation.endPage | 197 | - |
dc.identifier.bibliographicCitation | ONCOLOGY, Vol.53(3) : 192-197, 1996-05 | - |
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