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Admission Hyperglycemia as a Predictor of Mortality in Acute Heart Failure: Comparison between the Diabetics and Non-Diabetics

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dc.contributor.author강석민-
dc.date.accessioned2021-05-21T17:11:08Z-
dc.date.available2021-05-21T17:11:08Z-
dc.date.issued2020-01-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182755-
dc.description.abstractBackground: To investigate the impact of admission hyperglycemia (HGL) on in-hospital death (IHD) and 1-year mortality in acute heart failure (AHF) patients with or without diabetes mellitus (DM). Methods: Among 5625 AHF patients enrolled in a nationwide registry, 5541 patients were divided into four groups based on the presence of admission HGL and diabetes mellitus (DM). Admission HGL was defined as admission glucose level > 200 mg/dL. IHD and 1-year mortality were compared. Results: IHD developed in 269 patients (4.9%), and 1-year death developed in 1220 patients (22.2%). DM was a significant predictor of 1-year death (24.8% in DM vs. 20.5% in non-DM, p < 0.001), but not for IHD. Interestingly, admission HGL was a significant predictor of both IHD (7.6% vs. 4.2%, p < 0.001) and 1-year death (26.2% vs. 21.3%, p = 0.001). Admission HGL was a significant predictor of IHD in both DM and non-DM group, whereas admission HGL was a significant predictor of 1-year death only in non-DM (27.8% vs. 19.9%, p = 0.003), but not in DM group. In multivariate analysis, admission HGL was an independent predictor of 1-year mortality in non-DM patients (HR 1.32, 95% CI 1.03-1.69, p = 0.030). Conclusion: Admission HGL was a significant predictor of IHD and 1-year death in patients with AHF, whereas DM was only a predictor of 1-year death. Admission HGL was an independent predictor of 1-year mortality in non-DM patients with AHF, but not in DM patients. Careful monitoring and intensive medical therapy should be considered in AHF patients with admission HGL, regardless of DM.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfJOURNAL OF CLINICAL MEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAdmission Hyperglycemia as a Predictor of Mortality in Acute Heart Failure: Comparison between the Diabetics and Non-Diabetics-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJae Yeong Cho-
dc.contributor.googleauthorKye Hun Kim-
dc.contributor.googleauthorSang Eun Lee-
dc.contributor.googleauthorHyun-Jai Cho-
dc.contributor.googleauthorHae-Young Lee-
dc.contributor.googleauthorJin-Oh Choi-
dc.contributor.googleauthorEun-Seok Jeon-
dc.contributor.googleauthorMin-Seok Kim-
dc.contributor.googleauthorJae-Joong Kim-
dc.contributor.googleauthorKyung-Kuk Hwang-
dc.contributor.googleauthorShung Chull Chae-
dc.contributor.googleauthorSang Hong Baek-
dc.contributor.googleauthorSeok-Min Kang-
dc.contributor.googleauthorDong-Ju Choi-
dc.contributor.googleauthorByung-Su Yoo-
dc.contributor.googleauthorYoungkeun Ahn-
dc.contributor.googleauthorHyun-Young Park-
dc.contributor.googleauthorMyeong-Chan Cho-
dc.contributor.googleauthorByung-Hee Oh-
dc.identifier.doi10.3390/jcm9010149-
dc.contributor.localIdA00037-
dc.relation.journalcodeJ03556-
dc.identifier.eissn2077-0383-
dc.identifier.pmid31935874-
dc.subject.keywordacute heart failure-
dc.subject.keyworddiabetes mellitus-
dc.subject.keywordhyperglycemia-
dc.subject.keywordmortality-
dc.contributor.alternativeNameKang, Seok Min-
dc.contributor.affiliatedAuthor강석민-
dc.citation.volume9-
dc.citation.number1-
dc.citation.startPage149-
dc.identifier.bibliographicCitationJOURNAL OF CLINICAL MEDICINE, Vol.9(1) : 149, 2020-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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