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Impact of comorbid asthma on severity of coronavirus disease (COVID-19)
DC Field | Value | Language |
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dc.contributor.author | 정지예 | - |
dc.date.accessioned | 2021-05-21T17:08:14Z | - |
dc.date.available | 2021-05-21T17:08:14Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182725 | - |
dc.description.abstract | The severity of the coronavirus disease (COVID-19) is associated with various comorbidities. However, no studies have yet demonstrated the potential risk of respiratory failure and mortality in COVID-19 patients with pre-existing asthma. We selected 7272 adult COVID-19 patients from the Korean Health Insurance Review and Assessment COVID-19 database for this nationwide retrospective cohort study. Among these, 686 patients with asthma were assessed by their severities and evaluated by the clinical outcome of COVID-19 compared to patients without asthma. Of 7272 adult COVID-19 patients, 686 with asthma and 6586 without asthma were compared. Asthma was not a significant risk factor for respiratory failure or mortality among all COVID-19 patients (odds ratio [OR] = 0.99, P = 0.997 and OR = 1.06, P = 0.759) after adjusting for age, sex, and the Charlson comorbidity score. However, a history of acute exacerbation (OR = 2.63, P = 0.043) was significant risk factors for death among COVID-19 patients with asthma. Asthma is not a risk factor for poor prognosis of COVID-19. However, asthma patients who had any experience of acute exacerbation in the previous year before COVID-19 showed higher COVID-19-related mortality, especially in case of old age and male sex. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Asthma / mortality* | - |
dc.subject.MESH | Asthma / therapy | - |
dc.subject.MESH | COVID-19 / mortality* | - |
dc.subject.MESH | COVID-19 / therapy | - |
dc.subject.MESH | Comorbidity | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Respiratory Insufficiency / mortality* | - |
dc.subject.MESH | Respiratory Insufficiency / therapy | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | SARS-CoV-2* | - |
dc.title | Impact of comorbid asthma on severity of coronavirus disease (COVID-19) | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Sang Chul Lee | - |
dc.contributor.googleauthor | Kang Ju Son | - |
dc.contributor.googleauthor | Chang Hoon Han | - |
dc.contributor.googleauthor | Ji Ye Jung | - |
dc.contributor.googleauthor | Seon Cheol Park | - |
dc.identifier.doi | 10.1038/s41598-020-77791-8 | - |
dc.contributor.localId | A03735 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 33311519 | - |
dc.contributor.alternativeName | Jung, Ji Ye | - |
dc.contributor.affiliatedAuthor | 정지예 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 21805 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.10(1) : 21805, 2020-12 | - |
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