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Profiles of Extrapulmonary Nontuberculous Mycobacteria Infections and Predictors for Species: A Multicenter Retrospective Study

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dc.contributor.author구남수-
dc.contributor.author김정호-
dc.contributor.author송영구-
dc.contributor.author안진영-
dc.contributor.author염준섭-
dc.contributor.author정수진-
dc.contributor.author최준용-
dc.contributor.author김준형-
dc.contributor.author성혜-
dc.date.accessioned2021-05-21T16:49:59Z-
dc.date.available2021-05-21T16:49:59Z-
dc.date.issued2020-11-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182583-
dc.description.abstractExtrapulmonary nontuberculous mycobacteria (NTM) infections contribute to morbidity and mortality worldwide. However, studies about extrapulmonary NTM infections have been limited. Therefore, we aim to describe the diversity of extrapulmonary NTM infections and identify predictors for species. Information regarding diversity of NTM isolates, antimicrobial susceptibility testing, treatment regimens, and outcomes were collected from four tertiary care centers in South Korea. Comparisons were made between patients with rapidly growing mycobacteria (RGM) and slowly growing mycobacteria (SGM) infections. A total of 117 patients (46 males vs. 71 females) were included. Skin and soft tissue infections (SSTIs) predominated (34.2%), followed by bone and joint infections (28.2%). In SSTIs, RGM species were predominantly identified (26/28, 92.9%), whereas SGM species were mainly identified in bone and joint infections (18/26, 69.2%), and the difference of isolated sites was verified by a post hoc test (p < 0.001). Multivariable regression analysis revealed that male sex (vs. female sex; OR 5.30, CI 1.35-24.26, p = 0.020) and bone and joint infections (vs. SSTIs; OR 18.10, CI 3.28-157.07, p = 0.002) were predictors of SGM infections, whereas the opposite was observed for RGM infections. Bone and joint infections and male sex were predictors for SGM infections, whereas SSTIs and female sex were predictors for RGM infections.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherMDPI AG-
dc.relation.isPartOfPATHOGENS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleProfiles of Extrapulmonary Nontuberculous Mycobacteria Infections and Predictors for Species: A Multicenter Retrospective Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJung Ho Kim-
dc.contributor.googleauthorIn Young Jung-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorEun Jin Kim-
dc.contributor.googleauthorJun Hyoung Kim-
dc.contributor.googleauthorWoon Ji Lee-
dc.contributor.googleauthorHye Seong-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorJun Yong Choi-
dc.contributor.googleauthorJoon-Sup Yeom-
dc.contributor.googleauthorYoung Goo Song-
dc.identifier.doi10.3390/pathogens9110949-
dc.contributor.localIdA00189-
dc.contributor.localIdA00902-
dc.contributor.localIdA02037-
dc.contributor.localIdA02267-
dc.contributor.localIdA02353-
dc.contributor.localIdA03638-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ03983-
dc.identifier.eissn2076-0817-
dc.identifier.pmid33202553-
dc.subject.keywordnontuberculous mycobacteria-
dc.subject.keywordrapidly growing mycobacteria-
dc.subject.keywordslowly growing mycobacteria-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김정호-
dc.contributor.affiliatedAuthor송영구-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor염준섭-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor최준용-
dc.citation.volume9-
dc.citation.number11-
dc.citation.startPage949-
dc.identifier.bibliographicCitationPATHOGENS, Vol.9(11) : 949, 2020-11-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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