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Cellular Senescence and Inflammaging in the Skin Microenvironment
DC Field | Value | Language |
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dc.contributor.author | 김태균 | - |
dc.contributor.author | 이영인 | - |
dc.contributor.author | 이주희 | - |
dc.date.accessioned | 2021-04-29T17:39:33Z | - |
dc.date.available | 2021-04-29T17:39:33Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 1661-6596 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182455 | - |
dc.description.abstract | Cellular senescence and aging result in a reduced ability to manage persistent types of inflammation. Thus, the chronic low-level inflammation associated with aging phenotype is called “inflammaging”. Inflammaging is not only related with age-associated chronic systemic diseases such as cardiovascular disease and diabetes, but also skin aging. As the largest organ of the body, skin is continuously exposed to external stressors such as UV radiation, air particulate matter, and human microbiome. In this review article, we present mechanisms for accumulation of senescence cells in different compartments of the skin based on cell types, and their association with skin resident immune cells to describe changes in cutaneous immunity during the aging process. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.publisher | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Cellular Senescence and Inflammaging in the Skin Microenvironment | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학교실) | - |
dc.contributor.googleauthor | Young In Lee | - |
dc.contributor.googleauthor | Sooyeon Choi | - |
dc.contributor.googleauthor | Won Seok Roh | - |
dc.contributor.googleauthor | Ju Hee Lee | - |
dc.contributor.googleauthor | Tae-Gyun Kim | - |
dc.identifier.doi | 10.3390/ijms22083849 | - |
dc.contributor.localId | A05324 | - |
dc.contributor.localId | A05880 | - |
dc.contributor.localId | A03171 | - |
dc.relation.journalcode | J01133 | - |
dc.identifier.eissn | 1422-0067 | - |
dc.subject.keyword | inflammaging | - |
dc.subject.keyword | senescence | - |
dc.subject.keyword | skin | - |
dc.subject.keyword | fibroblasts | - |
dc.subject.keyword | keratinocytes | - |
dc.subject.keyword | melanocytes | - |
dc.subject.keyword | immune cells | - |
dc.contributor.alternativeName | Kim, Tae-Gyun | - |
dc.contributor.affiliatedAuthor | 김태균 | - |
dc.contributor.affiliatedAuthor | 이영인 | - |
dc.contributor.affiliatedAuthor | 이주희 | - |
dc.citation.volume | 22 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 3849 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, Vol.22(8) : 3849, 2021-04 | - |
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