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Different roles of surveillance positron emission tomography according to the histologic subtype of non-Hodgkin's lymphoma
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김수정 | - |
dc.contributor.author | 김유리 | - |
dc.contributor.author | 김진석 | - |
dc.contributor.author | 민유홍 | - |
dc.contributor.author | 양우익 | - |
dc.contributor.author | 장지은 | - |
dc.contributor.author | 정준원 | - |
dc.contributor.author | 정해림 | - |
dc.contributor.author | 조응혁 | - |
dc.contributor.author | 조현수 | - |
dc.contributor.author | 김윤덕 | - |
dc.date.accessioned | 2021-04-29T17:31:41Z | - |
dc.date.available | 2021-04-29T17:31:41Z | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182392 | - |
dc.description.abstract | Background/aims: Although the use of surveillance 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is discouraged in patients with diffuse large B-cell lymphoma, its usefulness in different subtypes has not been thoroughly investigated. Methods: We retrospectively evaluated 157 patients who showed positive results on surveillance FDG-PET/CT every 6 months following complete response for up to 5 years. All of the patients also underwent biopsies. Results: Seventy-eight (49.6%) of 157 patients had true positive results; the remaining 79 (50.3%), including eight (5.1%) with secondary malignancies, were confirmed to yield false positive results. Among the 78 patients with true positive results, the disease in seven (8.9%) had transformed to a different subtype. The positive predictive value (PPV) of FDG-PET/CT for aggressive B-cell non-Hodgkin's lymphoma (NHL) was lower than that for indolent B-cell or aggressive T-cell NHL (p = 0.003 and p = 0.018, respectively), especially in patients with a low/low-intermediate international prognostic index (IPI) upon a positive PET/CT finding. On the other hand, indolent B-cell and aggressive T-cell NHL patients showed PPVs of > 60%, including those with low/low-intermediate secondary IPIs. Conclusion: The role of FDG-PET/CT surveillance is limited, and differs according to the lymphoma subtype. FDG-PET/CT may be useful in detecting early relapse in patients with aggressive T-cell NHL, including those with low/low-intermediate risk secondary IPI; as already known, FDG-PET/CT has no role in aggressive B-cell NHL. Repeat biopsy should be performed to discriminate relapse or transformation from false positive findings in patients with positive surveillance FDG-PET/CT results. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Korean Association of Internal Medicine | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Different roles of surveillance positron emission tomography according to the histologic subtype of non-Hodgkin's lymphoma | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Yu Ri Kim | - |
dc.contributor.googleauthor | Soo-Jeong Kim | - |
dc.contributor.googleauthor | June-Won Cheong | - |
dc.contributor.googleauthor | Yundeok Kim | - |
dc.contributor.googleauthor | Ji Eun Jang | - |
dc.contributor.googleauthor | Hyunsoo Cho | - |
dc.contributor.googleauthor | Haerim Chung | - |
dc.contributor.googleauthor | Yoo Hong Min | - |
dc.contributor.googleauthor | Woo Ick Yang | - |
dc.contributor.googleauthor | Arthur Cho | - |
dc.contributor.googleauthor | Jin Seok Kim | - |
dc.identifier.doi | 10.3904/kjim.2019.376 | - |
dc.contributor.localId | A00633 | - |
dc.contributor.localId | A00779 | - |
dc.contributor.localId | A01017 | - |
dc.contributor.localId | A01407 | - |
dc.contributor.localId | A02300 | - |
dc.contributor.localId | A03477 | - |
dc.contributor.localId | A03729 | - |
dc.contributor.localId | A04674 | - |
dc.contributor.localId | A03887 | - |
dc.contributor.localId | A03929 | - |
dc.relation.journalcode | J02883 | - |
dc.identifier.eissn | 2005-6648 | - |
dc.identifier.pmid | 32550718 | - |
dc.subject.keyword | Positron emission tomography computed tomography | - |
dc.subject.keyword | Sensitivity and specificity | - |
dc.contributor.alternativeName | Kim, Soo Jeong | - |
dc.contributor.affiliatedAuthor | 김수정 | - |
dc.contributor.affiliatedAuthor | 김유리 | - |
dc.contributor.affiliatedAuthor | 김진석 | - |
dc.contributor.affiliatedAuthor | 민유홍 | - |
dc.contributor.affiliatedAuthor | 양우익 | - |
dc.contributor.affiliatedAuthor | 장지은 | - |
dc.contributor.affiliatedAuthor | 정준원 | - |
dc.contributor.affiliatedAuthor | 정해림 | - |
dc.contributor.affiliatedAuthor | 조응혁 | - |
dc.contributor.affiliatedAuthor | 조현수 | - |
dc.citation.volume | 19 | - |
dc.citation.number | 36 Suppl 1 | - |
dc.citation.startPage | S245 | - |
dc.citation.endPage | S252 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, Vol.19(36 Suppl 1) : S245-S252, 2021-03 | - |
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