Cited 8 times in
The behavior of residual tumors following incomplete surgical resection for vestibular schwannomas
DC Field | Value | Language |
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dc.contributor.author | 박소희 | - |
dc.contributor.author | 박현호 | - |
dc.contributor.author | 이규성 | - |
dc.contributor.author | 장원석 | - |
dc.contributor.author | 장종희 | - |
dc.contributor.author | 정현호 | - |
dc.contributor.author | 홍창기 | - |
dc.date.accessioned | 2021-04-29T17:27:37Z | - |
dc.date.available | 2021-04-29T17:27:37Z | - |
dc.date.issued | 2021-02 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182352 | - |
dc.description.abstract | The management of vestibular schwannoma (VS) with residual tumor following incomplete resection remains controversial and little is known regarding postoperative tumor volume changes. The behavior of residual tumors was analyzed for 111 patients who underwent surgery for newly diagnosed VS between September 2006 and July 2017. The postoperative tumor volume changes were assessed during a mean follow-up of 69 months (range 36-147 months). Fifty-three patients underwent imaging surveillance following incomplete resection. There was no residual tumor growth in 44 patients (83%). A significant regression of residual tumor volume was noted in the no growth group at postoperative 1 year (p = 0.028), 2 years (p = 0.012), but not from 3 years onwards. Significant predictors of regrowth were immediate postoperative tumor volume ≥ 0.7 cm3 (HR 10.5, p = 0.020) and residual tumor location other than the internal auditory canal (IAC) (HR 6.2, p = 0.026). The mean time to regrowth was 33 months (range 5-127 months). The 2-, 5-, and 10-year regrowth-free survival rates were 90.6%, 86.8%, and 83%, respectively. In conclusion, significant residual tumor regression could occur within 2 years for a VS with an immediate postoperative tumor volume less than 0.7 cm3 or residual tumor in IAC. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | The behavior of residual tumors following incomplete surgical resection for vestibular schwannomas | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Hun Ho Park | - |
dc.contributor.googleauthor | So Hee Park | - |
dc.contributor.googleauthor | Hyeong-Cheol Oh | - |
dc.contributor.googleauthor | Hyun-Ho Jung | - |
dc.contributor.googleauthor | Jong Hee Chang | - |
dc.contributor.googleauthor | Kyu-Sung Lee | - |
dc.contributor.googleauthor | Won Seok Chang | - |
dc.contributor.googleauthor | Chang-Ki Hong | - |
dc.identifier.doi | 10.1038/s41598-021-84319-1 | - |
dc.contributor.localId | A05904 | - |
dc.contributor.localId | A01750 | - |
dc.contributor.localId | A02682 | - |
dc.contributor.localId | A03454 | - |
dc.contributor.localId | A03470 | - |
dc.contributor.localId | A03775 | - |
dc.contributor.localId | A04445 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 33633337 | - |
dc.contributor.alternativeName | Park, So Hee | - |
dc.contributor.affiliatedAuthor | 박소희 | - |
dc.contributor.affiliatedAuthor | 박현호 | - |
dc.contributor.affiliatedAuthor | 이규성 | - |
dc.contributor.affiliatedAuthor | 장원석 | - |
dc.contributor.affiliatedAuthor | 장종희 | - |
dc.contributor.affiliatedAuthor | 정현호 | - |
dc.contributor.affiliatedAuthor | 홍창기 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 4665 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.11(1) : 4665, 2021-02 | - |
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