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Investigating the Relationship between Glaucoma Prevalence and Trabecular Meshwork Length

 Wungrak Choi  ;  Hyuna Cho  ;  Eun Woo Kim  ;  Hyoung Won Bae  ;  Chan Yun Kim  ;  Gong Je Seong 
 JOURNAL OF CLINICAL MEDICINE, Vol.10(5) : 1096, 2021-03 
Journal Title
Issue Date
anterior segment optical coherence tomography ; ethnicity ; glaucoma prevalence ; trabecular meshwork
Glaucoma is one of the most common causes of blindness worldwide, but the risk factors of glaucoma are yet to be fully understood. We investigated the relationship between the prevalence of glaucoma and trabecular meshwork (TM) length by comparing the mean TM length of a South Korean population with that of another ethnic population. We included 250 eyes of 125 patients who underwent anterior segment optical coherence tomography at Yonsei University Gangnam Severance Hospital between January 2015 and December 2017. We measured the distance from the scleral spur to Schwalbe's line in patients with open and closed angles and calculated the TM length using the open- and closed-angle ratios in the general population. The mean TM length of the patients in our study was 752 ± 116 μm. Considering the compensated data, the estimated true mean TM length in the Korean population was 793 ± 76 μm, which was similar to the mean TM length of a previously evaluated Hispanic population, but differed significantly from those of previously evaluated Asian (Chinese), Caucasian, and African-American populations (p < 0.05). Our results support the hypothesis that the development of glaucoma would be affected by TM length.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chan Yun(김찬윤) ORCID logo https://orcid.org/0000-0002-8373-9999
Bae, Hyoung Won(배형원) ORCID logo https://orcid.org/0000-0002-8421-5636
Seong, Gong Je(성공제) ORCID logo https://orcid.org/0000-0002-5456-4296
Choi, Wungrak(최웅락) ORCID logo https://orcid.org/0000-0002-3015-2502
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