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Differential Vascular Responses to New-Generation Drug-Eluting Stenting According to Clinical Presentation: Three-Month Optical Coherence Tomographic Study
DC Field | Value | Language |
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dc.contributor.author | 고영국 | - |
dc.contributor.author | 김병극 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 안철민 | - |
dc.contributor.author | 이승준 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 홍명기 | - |
dc.contributor.author | 홍성진 | - |
dc.date.accessioned | 2021-04-29T17:15:26Z | - |
dc.date.available | 2021-04-29T17:15:26Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 0003-3197 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/182249 | - |
dc.description.abstract | We evaluated early vascular responses after new-generation drug-eluting stent (DES) implantation. From 2 randomized trials, we identified 471 patients (138 patients with acute myocardial infarction [AMI] vs 333 patients with stable angina or unstable angina [SA/UA]) treated by DESs who underwent serial optical coherence tomography (OCT) from postprocedure to 3 months. At 3-month follow-up OCT, malapposed strut percentage was higher in AMI than in SA/UA (5.3% vs 0.7%, P < .001); it was markedly increased from postprocedure in AMI (2.0%-5.3%, P < .001), whereas it decreased in SA/UA (1.7%-0.7%, P < .001). Patients with AMI showed a higher risk of persistent (59% vs 37%; P < .001) or late-acquired malapposition (15% vs 8%; P = .04). Uncovered strut percentage at 3 months was also higher in AMI than in SA/UA (13.1% vs 6.7%, P < .001). The AMI presentation was the significant risk factor for both significant stent malapposition (SM, ≥200 μm; odds ratio [OR] = 3.45, CI = 1.85-7.14, P < .001) and uncovered stent (% uncovered struts >6.0%; OR = 2.44, CI = 1.35-4.76, P = .004), together with malapposed distance and postprocedural thrombi. Further, AMI presentation was the predictor for the occurrence of early period late-acquired and persistent malapposition. Serial OCT comparison analyses showed that patients with AMI compared with patients with SA/UA showed more delayed strut coverage, more severe degree SM or uncovered stents, and higher incidences of early period persistent or late-acquired SM. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Sage Publications | - |
dc.relation.isPartOf | ANGIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angina, Stable / diagnostic imaging | - |
dc.subject.MESH | Angina, Stable / therapy* | - |
dc.subject.MESH | Angina, Unstable / diagnostic imaging | - |
dc.subject.MESH | Angina, Unstable / therapy* | - |
dc.subject.MESH | Coronary Artery Disease / diagnostic imaging | - |
dc.subject.MESH | Coronary Artery Disease / therapy* | - |
dc.subject.MESH | Coronary Vessels / diagnostic imaging* | - |
dc.subject.MESH | Drug-Eluting Stents* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Infarction / diagnostic imaging | - |
dc.subject.MESH | Myocardial Infarction / therapy* | - |
dc.subject.MESH | Percutaneous Coronary Intervention / adverse effects | - |
dc.subject.MESH | Percutaneous Coronary Intervention / instrumentation* | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Randomized Controlled Trials as Topic | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Tomography, Optical Coherence* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Differential Vascular Responses to New-Generation Drug-Eluting Stenting According to Clinical Presentation: Three-Month Optical Coherence Tomographic Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Seung-Jun Lee | - |
dc.contributor.googleauthor | Sung-Jin Hong | - |
dc.contributor.googleauthor | Byeong-Keuk Kim | - |
dc.contributor.googleauthor | Chul-Min Ahn | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Young-Guk Ko | - |
dc.contributor.googleauthor | Donghoon Choi | - |
dc.contributor.googleauthor | Myeong-Ki Hong | - |
dc.contributor.googleauthor | Yangsoo Jang | - |
dc.identifier.doi | 10.1177/0003319720980607 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A00493 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A02269 | - |
dc.contributor.localId | A02927 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04391 | - |
dc.contributor.localId | A04403 | - |
dc.relation.journalcode | J00148 | - |
dc.identifier.eissn | 1940-1574 | - |
dc.identifier.pmid | 33342226 | - |
dc.identifier.url | https://journals.sagepub.com/doi/10.1177/0003319720980607 | - |
dc.subject.keyword | acute myocardial infarction | - |
dc.subject.keyword | drug-eluting stent | - |
dc.subject.keyword | neointimal coverage | - |
dc.subject.keyword | optical coherence tomography | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | 고영국 | - |
dc.contributor.affiliatedAuthor | 김병극 | - |
dc.contributor.affiliatedAuthor | 김중선 | - |
dc.contributor.affiliatedAuthor | 안철민 | - |
dc.contributor.affiliatedAuthor | 이승준 | - |
dc.contributor.affiliatedAuthor | 장양수 | - |
dc.contributor.affiliatedAuthor | 최동훈 | - |
dc.contributor.affiliatedAuthor | 홍명기 | - |
dc.contributor.affiliatedAuthor | 홍성진 | - |
dc.citation.volume | 72 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 381 | - |
dc.citation.endPage | 391 | - |
dc.identifier.bibliographicCitation | ANGIOLOGY, Vol.72(4) : 381-391, 2021-04 | - |
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