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Assessment of Image Quality for Selective Intracoronary Contrast-Injected CT Angiography in a Hybrid Angio-CT System: A Feasibility Study in Swine

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dc.contributor.author이병권-
dc.contributor.author장혁재-
dc.contributor.author정성희-
dc.date.accessioned2021-04-29T17:13:34Z-
dc.date.available2021-04-29T17:13:34Z-
dc.date.issued2021-03-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/182238-
dc.description.abstractPurpose: To compare image quality in selective intracoronary contrast-injected computed tomography angiography (Selective-CTA) with that in conventional intravenous contrast-injected CTA (IV-CTA). Materials and methods: Six pigs (35 to 40 kg) underwent both IV-CTA using an intravenous injection (60 mL) and Selective-CTA using an intracoronary injection (20 mL) through a guide-wire during/after percutaneous coronary intervention. Images of the common coronary artery were acquired. Scans were performed using a combined machine comprising an invasive coronary angiography suite and a 320-channel multi-slice CT scanner. Quantitative image quality parameters of CT attenuation, image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), mean lumen diameter (MLD), and mean lumen area (MLA) were measured and compared. Qualitative analysis was performed using intraclass correlation coefficient (ICC), which was calculated for analysis of interobserver agreement. Results: Quantitative image quality, determined by assessing the uniformity of CT attenuation (399.06 vs. 330.21, p<0.001), image noise (24.93 vs. 18.43, p<0.001), SNR (16.43 vs. 18.52, p=0.005), and CNR (11.56 vs. 13.46, p=0.002), differed significantly between IV-CTA and Selective-CTA. MLD and MLA showed no significant difference overall (2.38 vs. 2.44, p=0.068, 4.72 vs. 4.95, p=0.078). The density of contrast agent was significantly lower for selective-CTA (13.13 mg/mL) than for IV-CTA (400 mg/mL). Agreement between observers was acceptable (ICC=0.79±0.08). Conclusion: Our feasibility study in swine showed that compared to IV-CTA, Selective-CTA provides better image quality and requires less iodine contrast medium.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAnimals-
dc.subject.MESHComputed Tomography Angiography*-
dc.subject.MESHContrast Media / chemistry*-
dc.subject.MESHCoronary Angiography*-
dc.subject.MESHCoronary Vessels-
dc.subject.MESHFeasibility Studies-
dc.subject.MESHFemale-
dc.subject.MESHImage Enhancement*-
dc.subject.MESHImage Processing, Computer-Assisted-
dc.subject.MESHRadiation Dosage-
dc.subject.MESHSwine-
dc.titleAssessment of Image Quality for Selective Intracoronary Contrast-Injected CT Angiography in a Hybrid Angio-CT System: A Feasibility Study in Swine-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSeongmin Ha-
dc.contributor.googleauthorSunghee Jung-
dc.contributor.googleauthorHyung Bok Park-
dc.contributor.googleauthorSanghoon Shin-
dc.contributor.googleauthorReza Arsanjani-
dc.contributor.googleauthorYoungtaek Hong-
dc.contributor.googleauthorByoung Kwon Lee-
dc.contributor.googleauthorYeonggul Jang-
dc.contributor.googleauthorByunghwan Jeon-
dc.contributor.googleauthorSe Il Park-
dc.contributor.googleauthorHackjoon Shim-
dc.contributor.googleauthorHyuk Jae Chang-
dc.identifier.doi10.3349/ymj.2021.62.3.200-
dc.contributor.localIdA02793-
dc.contributor.localIdA03490-
dc.contributor.localIdA06057-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid33635009-
dc.subject.keywordComputed tomography angiography-
dc.subject.keywordcontrast media-
dc.subject.keywordimage quality enhancement-
dc.subject.keywordpercutaneous coronary intervention-
dc.contributor.alternativeNameLee, Byoung Kwon-
dc.contributor.affiliatedAuthor이병권-
dc.contributor.affiliatedAuthor장혁재-
dc.contributor.affiliatedAuthor정성희-
dc.citation.volume62-
dc.citation.number3-
dc.citation.startPage200-
dc.citation.endPage208-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.62(3) : 200-208, 2021-03-
Appears in Collections:
1. College of Medicine (의과대학) > BioMedical Science Institute (의생명과학부) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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